Experience

Polysciences, Inc.

• United States
• Biotechnology Research
• 100 - 200 Employee

• Senior Scientist II

  • Feb 2016 - Present

  Large scale synthesis of monomers and polymers. Research and development of the optimized process to ensure the reproducibility and quality from batch to batch. Large scale synthesis of monomers and polymers. Research and development of the optimized process to ensure the reproducibility and quality from batch to batch.



Wyzant

• United States
• Technology, Information and Internet
• 700 & Above Employee

• Private Tutor

  • Jan 2013 - Present

  My responsibilities include tutoring students at the high school or college level the fundamentals of Chemistry in courses that the student is enrolled. My responsibilities include tutoring students at the high school or college level the fundamentals of Chemistry in courses that the student is enrolled.



Isosciences LLC

• United States
• Chemical Manufacturing
• 1 - 100 Employee

• Senior Synthetic Chemist

  • Jun 2014 - Feb 2016

  Synthesis of complex molecules and incorporating stable label isotopes using modern synthetic chemistry. Synthesis of complex molecules and incorporating stable label isotopes using modern synthetic chemistry.



Merck

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Research Scientist

  • 2000 - 2013

  Design, synthesis, purification and characterization of novel drug target molecules and chemical intermediates. Utilized analysis of SAR and pharmacological data as well as multistep organic synthesis and modern chromatographic and spectroscopic techniques. Collaborated with drug metabolism and modeling groups to optimize drug properties and to progress compounds from lead optimization to safety trials producing awards, patents, and publications.

• Research Chemist

  • 1996 - 2000

  Provided independent route design and troubleshooting difficult synthetic chemistry problems. Collaborated to progress compounds from lead optimization to safety trials. Supported on-going formulations, safety, and efficacy studies by interpreting data for new chemical entities, metabolites, and chemical impurities. Optimized synthetic routes, and synthesized large scale quantities of requisite compounds. Prepared multi-gram quantities of crystalline materials to enable feasibility of pro-drug studies and evaluation of competitor's landscape. Contributed to three publications.

• Staff Chemist

  • 1994 - 1996

  Prepared key non-peptide oxytocin antagonists for the oxytocin receptor antagonist program. A key contribution was the incorporation of a pyridine N-oxide group into analogs which possessed good in vitro and in vivo potency, excellent oral bioavailability, good aqueous solubility and excellent selectivity against the human arginine vasopressin receptors.