Adviti Naik

Assistant Teaching Professor at Carnegie Mellon University in Qatar
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Contact Information
us****@****om
(386) 825-5501
Location
Doha, Qatar, QA
Languages
  • English -
  • German -
  • French -
  • Hindi -
  • Konkani -

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Experience

    • Qatar
    • Higher Education
    • 100 - 200 Employee
    • Assistant Teaching Professor
      • Aug 2023 - Present

    • Postdoctoral Researcher
      • Apr 2018 - Aug 2023

      Investigating the role of Cancer Testis Antigens (CTAs) in breast cancer oncogenesis and progression. Investigating the role of Cancer Testis Antigens (CTAs) in breast cancer oncogenesis and progression.

    • Postdoctoral Research Associate
      • Apr 2014 - Dec 2017

      I was involved in a clinical study of a breast cancer patient cohort in collaboration with the Sultan Qaboos Hospital in Oman, that identified a significant association of Neuropilin- 1 (NRP-1) and its ligand Placental Growth Factor (PlGF) in circulating plasma and tumour tissue with advanced nodal and metastatic breast cancer and triple negative breast cancer (TNBC). Furthermore, I was able to establish distinct gene expression profiles in circulating peripheral blood mononuclear cells (PBMCs)… Show more I was involved in a clinical study of a breast cancer patient cohort in collaboration with the Sultan Qaboos Hospital in Oman, that identified a significant association of Neuropilin- 1 (NRP-1) and its ligand Placental Growth Factor (PlGF) in circulating plasma and tumour tissue with advanced nodal and metastatic breast cancer and triple negative breast cancer (TNBC). Furthermore, I was able to establish distinct gene expression profiles in circulating peripheral blood mononuclear cells (PBMCs) that are cancer-specific and key molecules VEGFR3 and PLXNA1 that can distinguish TNBC from other tumour molecular types. I was also able to identify novel oncogenes and tumour suppressors associated with NRP-1 expression, in addition to dissecting the downstream signaling cascade of NRP-1 in driving tumourigenesis and chemo-resistance in breast cancer cellular models. Show less I was involved in a clinical study of a breast cancer patient cohort in collaboration with the Sultan Qaboos Hospital in Oman, that identified a significant association of Neuropilin- 1 (NRP-1) and its ligand Placental Growth Factor (PlGF) in circulating plasma and tumour tissue with advanced nodal and metastatic breast cancer and triple negative breast cancer (TNBC). Furthermore, I was able to establish distinct gene expression profiles in circulating peripheral blood mononuclear cells (PBMCs)… Show more I was involved in a clinical study of a breast cancer patient cohort in collaboration with the Sultan Qaboos Hospital in Oman, that identified a significant association of Neuropilin- 1 (NRP-1) and its ligand Placental Growth Factor (PlGF) in circulating plasma and tumour tissue with advanced nodal and metastatic breast cancer and triple negative breast cancer (TNBC). Furthermore, I was able to establish distinct gene expression profiles in circulating peripheral blood mononuclear cells (PBMCs) that are cancer-specific and key molecules VEGFR3 and PLXNA1 that can distinguish TNBC from other tumour molecular types. I was also able to identify novel oncogenes and tumour suppressors associated with NRP-1 expression, in addition to dissecting the downstream signaling cascade of NRP-1 in driving tumourigenesis and chemo-resistance in breast cancer cellular models. Show less

    • Slovenia
    • Higher Education
    • 500 - 600 Employee
    • Young Researcher (PhD student)
      • Oct 2010 - Dec 2013

      I successfully completed a PhD in Sytems Biology, wherein I was involved in modelling metabolic pathways important in the pathogenesis of Non-Alcoholic Fatty Liver Disease (NAFLD). Skills developed: Modelling and simulation of biological networks, model validation techniques, in vitro metabolic flux analysis, Machine learning algorithms and techniques I successfully completed a PhD in Sytems Biology, wherein I was involved in modelling metabolic pathways important in the pathogenesis of Non-Alcoholic Fatty Liver Disease (NAFLD). Skills developed: Modelling and simulation of biological networks, model validation techniques, in vitro metabolic flux analysis, Machine learning algorithms and techniques

    • United Kingdom
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Bioscience Placement Student
      • Sep 2009 - Sep 2010

      I carried out my Masters degree project in industry based in the in vivo Cancer Department at AstraZeneca, Alderley Park. My project involved the pharmacodynamic analysis of cytotoxic agents to design mechanistic combination therapy in breast cancer models. Skills acquired: Molecular biology techniques (Western blotting, Immunohistochemistry, ELISA, gene expression analysis on Fluidigm platform), experience on breast cancer cell models and tumour analysis, Data handling and analysis. I carried out my Masters degree project in industry based in the in vivo Cancer Department at AstraZeneca, Alderley Park. My project involved the pharmacodynamic analysis of cytotoxic agents to design mechanistic combination therapy in breast cancer models. Skills acquired: Molecular biology techniques (Western blotting, Immunohistochemistry, ELISA, gene expression analysis on Fluidigm platform), experience on breast cancer cell models and tumour analysis, Data handling and analysis.

    • Higher Education
    • 700 & Above Employee
    • Summer Work Experience Studentship
      • Aug 2007 - Oct 2007

      I investigated the phospho-status of the Rrp47 protein, which is an accessory protein to cellular exosomes involved in RNA surveillance. The project involved techniques such as protein expression , purification and kinase assays. I investigated the phospho-status of the Rrp47 protein, which is an accessory protein to cellular exosomes involved in RNA surveillance. The project involved techniques such as protein expression , purification and kinase assays.

Education

  • University of Tuebingen
    Doctor of Philosophy (PhD), Systems Biology
    2010 - 2013
  • The University of Sheffield
    MSc, Genetics and Molecular Cell Biology
    2006 - 2010

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