Experience

Cirqle Biomedical

• Denmark
• Biotechnology
• 1 - 100 Employee

• R&D Scientist

  • Nov 2022 - Present

  Design of vaginal gel for on demand contraception based on the reinforcement of the cervical mucus to make temporarily impenetrable to sperm - Formulation of biodegradable gel - Organisation and execution of in vitro tests (drug delivery and rheological assays) - Join collaboration with in vivo applications and observations - Mucin - polysaccharide interaction - Supervision of junior scientist Design of vaginal gel for on demand contraception based on the reinforcement of the cervical mucus to make temporarily impenetrable to sperm - Formulation of biodegradable gel - Organisation and execution of in vitro tests (drug delivery and rheological assays) - Join collaboration with in vivo applications and observations - Mucin - polysaccharide interaction - Supervision of junior scientist



ADOCIA

• France
• Biotechnology Research
• 1 - 100 Employee

• Research Scientist

  • Feb 2022 - Oct 2022

  Design of implants and long-acting injectables (LAIs) for various application in obesity, contraception or cell therapy - Synthesis, characterisation, formulation of non-biodegradable hydrogels - Organisation of in vitro tests (In vitro drug delivery and rheological assays) - Representative scientist in the animal laboratories during non-clinical trials - Technical project leader - Active in the Formulation department. Insight in the chemistry, analytical, PK/PD and pre-clinical departments Show less



University of Montpellier

• France
• Higher Education
• 700 & Above Employee

• PhD in Chemistry and Physics of Polymers and Materials

  • Nov 2017 - Sep 2021

  "New copolymers based on poly(dopamine) for the sustained delivery of active pharmaceutical ingredient to the eye by intravitreal administration" PhD thesis under joint supervision with Biomolecules Institute Max Mousseron (department of Polymers for Health and Biomaterials, Montpellier, France) and the international pharmaceutical company F.Hoffmann-La Roche (Basel, Switzerland). As the main tasks: - Development of novel functional copolymers - Design of injectable solid or liquid formulations for intravitreal (IVT) administration - Evaluation of the formulations' physical properties during the manufacturing and degradation processes - Evaluation of the stability of APIs (small molecules drugs and proteins) in formulations - in vitro / ex-vivo release profiles of APIs - Conduct of the in vitro cytotoxicity assays on formulations - Collaboration with postdocs and senior scientists from Basel Laboratory skills: Synthesis of monomers and polymers by ROP, ATRP, oxidation, chemical modification. Manufacturing processes of polymers. Release experiments of APIs. Biological evaluations. Analytical technics: SEC, 1H NMR, DOSY NMR, DSC, TGA, UV spectrometer, HPLC, BCA, contact angle, cell culture (viability assays). Project management: Mentored and trained students, planned and organized meetings, scientific and technical monitoring, wrote monthly reports and scientific articles. Software: Origin, Chemdraw, LabSolution, TopSpin, MestReNova, Show less



Arkema

• France
• Chemical Manufacturing
• 700 & Above Employee

• Research Internship

  • Apr 2017 - Sep 2017

  Synthesis and characterization of new acrylate-based copolymers and formulation of composite matrices for improvement in adhesion of Li-ion batteries Synthesis and characterization of new acrylate-based copolymers and formulation of composite matrices for improvement in adhesion of Li-ion batteries