Biomedical/Mechanical engineer

• May 2022 - Present

Graduate Research Assistant at Cardiovascular Biomechanics Lab

• Aug 2016 - Jul 2022

• Obtained the porcine and ovine aortas material properties initial guesses from biaxial stretching data, and optimized the material properties with Isight based on DIC measurement. • Participated in in-vitro DIC tests of CoreValve and SAPIEN 3 devices, found the optimized leaflet material properties in Fung anisotropic hyperelastic model. • Designed and prototyped various fixture designs for pulse duplicator testings, obtained the pressure and flow rate data under different… Show more • Obtained the porcine and ovine aortas material properties initial guesses from biaxial stretching data, and optimized the material properties with Isight based on DIC measurement. • Participated in in-vitro DIC tests of CoreValve and SAPIEN 3 devices, found the optimized leaflet material properties in Fung anisotropic hyperelastic model. • Designed and prototyped various fixture designs for pulse duplicator testings, obtained the pressure and flow rate data under different conditions for multiple TAV devices. • Conducted structural analyses of transcatheter aortic valve devices in different configurations, such as the geometry in the bicuspid aortic valve patients and the geometry with regional under expanded leaflet, and validated the results with pulse duplicator testing. • Performed a hemodynamic analysis using one-way FSI simulation on transcatheter aortic valve devices in ABAQUS and ANSYS Fluent, investigated the blood statics on the artificial leaflets to evaluate the thrombosis risk, validated the result with 2D PIV testing. • Reconstructed the ovine ascending aorta geometry through RapidWorks, SolidWorks, and HyperMesh according to DIC measurement and studied the mechanical effect of surgical adhesives on ascending thoracic aortic aneurysm replacement via FEA. Show less • Obtained the porcine and ovine aortas material properties initial guesses from biaxial stretching data, and optimized the material properties with Isight based on DIC measurement. • Participated in in-vitro DIC tests of CoreValve and SAPIEN 3 devices, found the optimized leaflet material properties in Fung anisotropic hyperelastic model. • Designed and prototyped various fixture designs for pulse duplicator testings, obtained the pressure and flow rate data under different… Show more • Obtained the porcine and ovine aortas material properties initial guesses from biaxial stretching data, and optimized the material properties with Isight based on DIC measurement. • Participated in in-vitro DIC tests of CoreValve and SAPIEN 3 devices, found the optimized leaflet material properties in Fung anisotropic hyperelastic model. • Designed and prototyped various fixture designs for pulse duplicator testings, obtained the pressure and flow rate data under different conditions for multiple TAV devices. • Conducted structural analyses of transcatheter aortic valve devices in different configurations, such as the geometry in the bicuspid aortic valve patients and the geometry with regional under expanded leaflet, and validated the results with pulse duplicator testing. • Performed a hemodynamic analysis using one-way FSI simulation on transcatheter aortic valve devices in ABAQUS and ANSYS Fluent, investigated the blood statics on the artificial leaflets to evaluate the thrombosis risk, validated the result with 2D PIV testing. • Reconstructed the ovine ascending aorta geometry through RapidWorks, SolidWorks, and HyperMesh according to DIC measurement and studied the mechanical effect of surgical adhesives on ascending thoracic aortic aneurysm replacement via FEA. Show less

R & D Engineering Intern

• Jun 2019 - Sep 2019

• Worked with cross-functional team in neurovascular (NV) business group on a localization project, transferred a product line to China following both CFDA and FDA regulations, and familiarized the technology behind the NV product and related requirements. • Reviewed the previous design and the feedback from the physicians, brainstormed and drafted patents for two projects in NV and ENT groups based on user input with 3D modeling and 2D drawings. • Collaborated with the NV & ENT group in… Show more • Worked with cross-functional team in neurovascular (NV) business group on a localization project, transferred a product line to China following both CFDA and FDA regulations, and familiarized the technology behind the NV product and related requirements. • Reviewed the previous design and the feedback from the physicians, brainstormed and drafted patents for two projects in NV and ENT groups based on user input with 3D modeling and 2D drawings. • Collaborated with the NV & ENT group in testing, learnt the validation procedure for both Class II and Class III medical devices. • Tutored the marketing and sales team members the neurovascular product and R&D procedures, facilitated them understanding the products to better introduce the products to the customers. Show less • Worked with cross-functional team in neurovascular (NV) business group on a localization project, transferred a product line to China following both CFDA and FDA regulations, and familiarized the technology behind the NV product and related requirements. • Reviewed the previous design and the feedback from the physicians, brainstormed and drafted patents for two projects in NV and ENT groups based on user input with 3D modeling and 2D drawings. • Collaborated with the NV & ENT group in… Show more • Worked with cross-functional team in neurovascular (NV) business group on a localization project, transferred a product line to China following both CFDA and FDA regulations, and familiarized the technology behind the NV product and related requirements. • Reviewed the previous design and the feedback from the physicians, brainstormed and drafted patents for two projects in NV and ENT groups based on user input with 3D modeling and 2D drawings. • Collaborated with the NV & ENT group in testing, learnt the validation procedure for both Class II and Class III medical devices. • Tutored the marketing and sales team members the neurovascular product and R&D procedures, facilitated them understanding the products to better introduce the products to the customers. Show less

Research Assistant at Zhu Lab

• Jul 2013 - Aug 2014

• Facilitated in a project using yeast as a model to study the effects of mutations in Cu, Zn-superoxide dismutase (SOD1) on neurodegenerative disease ALS, and analysed the change of morphology and movements after modifying yeast’s gene. • Teamed with PhD and master students in another project of drug effect test on mice, learnt the procedure and operation for drug testing on animal. • Facilitated in a project using yeast as a model to study the effects of mutations in Cu, Zn-superoxide dismutase (SOD1) on neurodegenerative disease ALS, and analysed the change of morphology and movements after modifying yeast’s gene. • Teamed with PhD and master students in another project of drug effect test on mice, learnt the procedure and operation for drug testing on animal.

Research Assistant at National Key Laboratory of Biology Engineering

• Mar 2013 - Jun 2013

• Performed a project related to phospholipase and strengthened the knowledge of protein preparation. • Compared and evaluated culture mediums for yeast by feeding yeast various categories of nitrogen and carbon sources, developed the best combination for yeast culturing. • Performed a project related to phospholipase and strengthened the knowledge of protein preparation. • Compared and evaluated culture mediums for yeast by feeding yeast various categories of nitrogen and carbon sources, developed the best combination for yeast culturing.

Operation Intern

• Dec 2012 - Feb 2013

• Inspected finished products by series of experiments on the yeast in quality control department, obtained a good understanding of beverage industry. • Apprenticed with supervisors to learn brewery process and regulations, understood the importance of hygiene environment in the work place and had the ability to keep it. • Inspected finished products by series of experiments on the yeast in quality control department, obtained a good understanding of beverage industry. • Apprenticed with supervisors to learn brewery process and regulations, understood the importance of hygiene environment in the work place and had the ability to keep it.