Eoin Murphy
Associate Manufacturing at Genevant Sciences- Claim this Profile
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Bio
Credentials
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What Is Program Management?
LinkedInOct, 2022- Nov, 2024 -
Planning Your Career and Your Life
LinkedInSep, 2020- Nov, 2024
Experience
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Genevant Sciences
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Canada
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Biotechnology
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1 - 100 Employee
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Associate Manufacturing
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Jun 2022 - Present
Member of the Centralised Formulation Team (CFT) for the Lipid Encapsulation of mRNA to form Lipid Nanoparticles. Tangential Flow Ultrafiltration (TFU) of mRNA+Lipid stock solutions. Particle Formulation System (PFS) setup, adjustment and Calibrations for mRNA+Lipid Stock solution compounding. Si-RNA rehydration and formulation. Ribogreen Analysis for total mRNA+Lipid Encapsulation and Concentration. Zetasizer Analysis for Polydispersity Indexing. Member of the Centralised Formulation Team (CFT) for the Lipid Encapsulation of mRNA to form Lipid Nanoparticles. Tangential Flow Ultrafiltration (TFU) of mRNA+Lipid stock solutions. Particle Formulation System (PFS) setup, adjustment and Calibrations for mRNA+Lipid Stock solution compounding. Si-RNA rehydration and formulation. Ribogreen Analysis for total mRNA+Lipid Encapsulation and Concentration. Zetasizer Analysis for Polydispersity Indexing.
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STEMCELL Technologies
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Canada
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Biotechnology Research
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700 & Above Employee
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Manufacturing Technologist
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Nov 2021 - Jun 2022
Manufacturing Technologist for GMP Manufacturing suite, where the production of Cell culture media and supplements occurs. Production suites adhere to the following ISO standards: ISO-8, 7, 6 & 5. Tasks: Final Fill product Packaging of Basal Medium as well as stabilized feeder-free maintenance medium for pluripotent stem cells. BSA bag setup, charging and incubation. Aseptic fill of sterile Nalgene bottles in ISO 5 enclosure via Peristaltic pump setup. Manufacturing Technologist for GMP Manufacturing suite, where the production of Cell culture media and supplements occurs. Production suites adhere to the following ISO standards: ISO-8, 7, 6 & 5. Tasks: Final Fill product Packaging of Basal Medium as well as stabilized feeder-free maintenance medium for pluripotent stem cells. BSA bag setup, charging and incubation. Aseptic fill of sterile Nalgene bottles in ISO 5 enclosure via Peristaltic pump setup.
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The Janssen Pharmaceutical Companies of Johnson & Johnson
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Associate Scientist - Contract
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Dec 2020 - Oct 2021
Bio-Therapeutics Development, Analytical Development Laboratory - Separations, Barnahely, Cork. 1. Perform bioanalytical and physical tests according to procedures – HPLC. 2. Generation of data and interpretation of results within required due dates for release, stability and PPQ Validation. 3. Perform data review, interpretation, and trending. 4. Assist with method development and optimization. 5. Contribute to proper use, calibration, and maintenance of laboratory equipment. 6. Perform investigations, invalid assays, laboratory events and deviations. 7. Develop subject matter expertise on assigned analytical techniques. 8. An active role in Continuous Improvement, identify and drive improvement initiatives. High Performance Liquid Chromatography (HPLC) analysis of Monoclonal Antibodies, such as: Cetrelimab: A programmed Cell Death Receptor-1 (PD-1) Inhibitor. A product used for the induction of T-cell-mediated immune responses against tumor cells. Guselkumab: A monoclonal antibody against Interleukin-23, used for the treatment of plaque psoriasis. Show less
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Merck Life Science
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Germany
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Biotechnology Research
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700 & Above Employee
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Analytical Laboratory Analyst - CPG & Media - Contract.
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Oct 2018 - Dec 2020
Quality Control Analyst in the Controlled Pore Glass (CPG) and Media section of the Analytical Laboratory, which adheres to Good Manufacturing Practice (GMP) requirements. Main tasks include: 1: Cleanliness Assessment/Particulate matter testing of CPG samples. 2: Loss on drying (LOD) and Water content assessment of CPG samples. 3: The determination of the Porosity of CPG through the use of Poremaster equipment and machinery with the aid of Quantachrome Software and Devices. 4: The assessment of the Bulk Density of CPG. 5: Particle Size Analysis of CPG. 6: ELISA - Protein A Leakage assay. 7: Fourier Transform Infrared Spectroscopy (FTIR) analysis. 8: Human IgG static binding Capacity testing. 9: Western Blot testing. 10: SDS PAGE analysis on incoming proteins. Additional training on the principles of operation for the performance of High Performance Liquid Chromatography as well as Gas Chromatography testing. Show less
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Quiet Storm Surf Shop
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1 - 100 Employee
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Sales Assistant
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Jun 2018 - Sep 2018
J1 Visa job in Ocean City, Maryland, USA. Junior Supervisor and Customer Service assistant. J1 Visa job in Ocean City, Maryland, USA. Junior Supervisor and Customer Service assistant.
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Ryan's SuperValu
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Glanmire, Cork
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Customer Assistant
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May 2012 - May 2018
A part time Student job while I attended both Second and Third Level Education. Maintained the Lobbies and Multi-story Car parks as well as the Checkout area. A part time Student job while I attended both Second and Third Level Education. Maintained the Lobbies and Multi-story Car parks as well as the Checkout area.
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The Janssen Pharmaceutical Companies of Johnson & Johnson
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Intern
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Feb 2018 - Apr 2018
An internship as part of my Final Year project, where I worked on "The assessment of Water For Injection & Water Purified for Chemical Synthesis systems for Energy Conservation". This involved the Analysis and Assessment of the active water systems on site, to try and devise a viable method of reducing the energy consumption of these systems, which were used for the manufacture of both conventional Small Molecule API's as well as Parenteral products. Such examples include: Paliperidone Palmitate which is the API for an antipsychotic drug that requires sterile manufacture, Flunarizine Hydrochloride which is used as an adjuvant for the treatment of epilepsy & Rilpivirine which is an anti HIV drug. Show less
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The Janssen Pharmaceutical Companies of Johnson & Johnson
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Intern
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Mar 2017 - Sep 2017
A 7 Month Work placement / Internship in Janssen Pharmaceuticals Unlimited, a company associated with my field of study. While on work placement I acted as a trainee Chemistry and Microbiology Quality Control analyst, whereby I took part in various activities such as: 1: Environmental Monitoring in a Sterile Manufacturing Module (MOD3) - Gowning experience, Aseptic Techniques etc. 2: Equipment Calibration - Daily Calibrations and Checks which needed to be performed. 3: Sample Login - The login of Water samples coming from the Sterile Manufacture Module with the use of ELIMS software before being transferred to the Biologics site for testing. 4: Insoluble Matter testing - The assessment of solvent purity and composition, ensuring no foreign particles/contaminants were present as per specification criteria. 5: Laboratory technician duties - Solvent acquisition, General maintenance and housekeeping as well as the restocking of Laboratory consumables. 6: The Documentation of results and updates to Standard Operating Procedures (SOP). Student Work placement projects : 1: JSCI Energy Awareness Project - A dual site group project with the aim of improving awareness on the over-expenditure of energy onsite, generally trying to promote a culture of energy conservation as well as providing information on alternative forms of energy which may be used instead of fossil fuels and other conventional forms. 2: The Cost of Quality - An assessment of the expenditure in the Laboratories, on consumables, waste management and overall running costs. Show less
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Education
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2017 - 2018
Cork Institute of Technology
Bsc. Hons Pharmaceutical Biotechnology, Biotechnology -
2014 - 2017
Cork Institute of Technology
Bsc. Applied Biosciences with Biotechnology, Biotechnology
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