Lynn Nguyen
Senior Research Associate at Locanabio, Inc.- Claim this Profile
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Bio
Olga Batalov
Lynn is a dedicated researcher with a tenacious commitment to the projects she is tasked with and an assertive, spirited personality. Her involvement on the Team Building committee helps both develop and demonstrate her collaboration and interpersonal communication skills. She is fully devoted to the professional development and skill acquisition of her direct reports and, most importantly, is willing to stand up for and defend them at all costs. Accountability is very important to her, both in the sense of taking responsibility for her own actions and ensuring that others take responsibility for theirs. Her can-do attitude and willingness to commit the time and energy, which at times can be burdensome and go beyond reasonable expectations, to following through on her projects is awe-inspiring. There is never a dull day with her around, as the unbelievably high level of energy, generally positive or at least motivating, that she practically radiates at work is infectious.
Olga Batalov
Lynn is a dedicated researcher with a tenacious commitment to the projects she is tasked with and an assertive, spirited personality. Her involvement on the Team Building committee helps both develop and demonstrate her collaboration and interpersonal communication skills. She is fully devoted to the professional development and skill acquisition of her direct reports and, most importantly, is willing to stand up for and defend them at all costs. Accountability is very important to her, both in the sense of taking responsibility for her own actions and ensuring that others take responsibility for theirs. Her can-do attitude and willingness to commit the time and energy, which at times can be burdensome and go beyond reasonable expectations, to following through on her projects is awe-inspiring. There is never a dull day with her around, as the unbelievably high level of energy, generally positive or at least motivating, that she practically radiates at work is infectious.
Olga Batalov
Lynn is a dedicated researcher with a tenacious commitment to the projects she is tasked with and an assertive, spirited personality. Her involvement on the Team Building committee helps both develop and demonstrate her collaboration and interpersonal communication skills. She is fully devoted to the professional development and skill acquisition of her direct reports and, most importantly, is willing to stand up for and defend them at all costs. Accountability is very important to her, both in the sense of taking responsibility for her own actions and ensuring that others take responsibility for theirs. Her can-do attitude and willingness to commit the time and energy, which at times can be burdensome and go beyond reasonable expectations, to following through on her projects is awe-inspiring. There is never a dull day with her around, as the unbelievably high level of energy, generally positive or at least motivating, that she practically radiates at work is infectious.
Olga Batalov
Lynn is a dedicated researcher with a tenacious commitment to the projects she is tasked with and an assertive, spirited personality. Her involvement on the Team Building committee helps both develop and demonstrate her collaboration and interpersonal communication skills. She is fully devoted to the professional development and skill acquisition of her direct reports and, most importantly, is willing to stand up for and defend them at all costs. Accountability is very important to her, both in the sense of taking responsibility for her own actions and ensuring that others take responsibility for theirs. Her can-do attitude and willingness to commit the time and energy, which at times can be burdensome and go beyond reasonable expectations, to following through on her projects is awe-inspiring. There is never a dull day with her around, as the unbelievably high level of energy, generally positive or at least motivating, that she practically radiates at work is infectious.
Experience
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Locanabio, Inc.
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Research Associate
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Apr 2021 - Present
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Cibus
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United States
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Biotechnology Research
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100 - 200 Employee
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Senior Research Associate - Department of Molecular Discovery
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2015 - Apr 2021
Applied site-directed and random mutagenesis techniques to identify polymorphisms to develop desired traits. Utilize various expression systems such as E. coli, S. cerevisiae, A. tumefaciens, and A. thaliana. Screened libraries utilizing various molecular methods such as transient expression in N. benthamiana, colorimetric-based protein activity assays, in-gel activity assays and Yeast-Two-Hybrid- Characterized and validated induction of gene(s) in plant species against bacterial/fungal infection-- Employed site-directed mutagenesis (SDM) based on computational recommendations to change the enzymatic activity of genes of interest.-- Screened 30+ SDM mutants using transient expression in N. benthamiana for qualitative and quantitative assays that detects activity.-- From the mutations generated, identified polymorphism in gene of interest that changes the protein structure and functionally changes the enzymatic activity, which led to a capture of company IP.-- Identified mutations have been recognized as a novel gene editing trait.- Created an in-house multi-site saturated library of mutations (over 8,000 variants) and QC’d library with NGS.- Conducted random mutagenesis to generate a library of single nucleotide polymorphisms into gene of interest and evaluate for strong protein-protein interaction in Yeast Two-Hybrid screening.-- Identified 20 candidates from Yeast Two-Hybrid screening -- Performed transient expression in N. benthamiana for in planta validation of gene against pathogen effectors and found one candidate with desired effects when challenged with the effector.-- Confirmed expression of transiently expressed proteins in N. benthamiana using SDS-PAGE and Western Blot.- Supervised and mentored junior staff and wrote monthly and quarterly progress reports, present results and data to small research group as well as the company’s scientific team. Show less
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Research Associate - Molecular Biology
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Sep 2012 - 2015
Studied the effects of polymorphisms in stable transgenic A. thaliana lines for increase resistance to bacterial pathogens(s).- Performed floral dip infiltration technique to generated stable transgenic lines of A. thaliana with gene(s) of interest.- Conducted large-scale DNA/RNA isolation of transgenic material for molecular screening - copy number, and expression levels (qPCR and RT-PCR).- Grew transgenic material to F2 generation and perform bacterial titer assays.- Perform bacterial infiltration assay on generated transgenic A. thaliana.- Utilized statistical analysis to assess the effects of polymorphisms of gene(s) on bacterial titer/load in A. thaliana.- Record and maintained meticulous data files for statistical analysis.- Worked along a Research Specialist to drive results and studies.- Contributed writing sections and figures to monthly report. Show less
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Research Associate - Cell Biology
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Jun 2010 - Sep 2012
Research Associate, Department of Cellular Biology 2010 - 2013Participated in the research and development of producing non-transgenic traits in plants using Cibus’ Rapid Trait Development System (RTDS).- Executed experiments using RTDS into plant cell protoplast for desired trait.- Used aseptic techniques to initiate and maintain embryogenic material for cell culture experiments.- Prepared weekly tissue culture media and chemical reagents for the crop team. Show less
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Education
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2007 - 2012
University of California, San Diego
Bachelor of Science (B.S.), Human Biology
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