João Brás
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Bio
Credentials
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Academic Process Mining Expert
CelonisSep, 2021- Nov, 2024
Experience
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Glintt
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Portugal
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IT Services and IT Consulting
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500 - 600 Employee
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Product Owner
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Nov 2022 - Present
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Healthcare Consultant
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Sep 2021 - Oct 2022
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iCBR - Coimbra Institute for Clinical and Biomedical Research
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Portugal
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Higher Education
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1 - 100 Employee
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Clinical Researcher
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Apr 2021 - Jun 2021
As a member of this institute, and within the scope of the project, I investigated, in in vitro models of microglia cells (BV2), mechanisms associated with neuroinflammation in the context of exposure of adult animals to methylmercury toxicity. As a member of this institute, and within the scope of the project, I investigated, in in vitro models of microglia cells (BV2), mechanisms associated with neuroinflammation in the context of exposure of adult animals to methylmercury toxicity.
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Center for Neuroscience and Cell Biology, Coimbra
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Coimbra, Portugal
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Clinical Researcher
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Jun 2020 - Mar 2021
As a member of the Vectors and Gene Therapy research group, and within the scope of the project, I implemented a combined strategy, involving the manipulation of microRNAs and siRNAs and the lipidome of glioblastoma cells, using Stable Nucleic Acid Lipid Particles (SNALPs), to increase the susceptibility of this cancer to new generation chemotherapeutic agents (e.g., Axitinib) and thus contributing to the eradication of this pathology. As a member of the Vectors and Gene Therapy research group, and within the scope of the project, I implemented a combined strategy, involving the manipulation of microRNAs and siRNAs and the lipidome of glioblastoma cells, using Stable Nucleic Acid Lipid Particles (SNALPs), to increase the susceptibility of this cancer to new generation chemotherapeutic agents (e.g., Axitinib) and thus contributing to the eradication of this pathology.
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Center for Neuroscience and Cell Biology, Coimbra
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Coimbra e Região, Portugal
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Researcher MSc Candidate
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Jul 2018 - Oct 2019
For my MSc thesis, I joined the Vectors and Gene Therapy research group, and within the scope of the project, I established and characterized human Pluripotent Stem Cells derived Brain Organoids to model Machado‑Joseph Disease (MJD), concretely, whole‑brain organoids from human induced Pluripotent Stem Cells (hiPSCs), and midbrain/hindbrain organoids from human Neuroepithelial Stem Cells (hNESCs). For my MSc thesis, I joined the Vectors and Gene Therapy research group, and within the scope of the project, I established and characterized human Pluripotent Stem Cells derived Brain Organoids to model Machado‑Joseph Disease (MJD), concretely, whole‑brain organoids from human induced Pluripotent Stem Cells (hiPSCs), and midbrain/hindbrain organoids from human Neuroepithelial Stem Cells (hNESCs).
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Education
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NOVA IMS Information management school
Post-graduation in Digital Enterprise Management -
Faculty of Pharmacy of the University of Coimbra
Master of Science - MS, Pharmaceutical Biotechnology -
Faculty of Pharmacy of the University of Coimbra
Bachelor of Science - BS, Biomedical Pharmacy