Brian Longstreet
Chief Operating Officer at CorriXR Therapeutics- Claim this Profile
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Experience
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CorriXR Therapeutics
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United States
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Biotechnology Research
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1 - 100 Employee
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Chief Operating Officer
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Jan 2022 - Present
Newark, Delaware, United States Senior Executive Leader helping build an early stage biotechnology company. Focused on all key areas of company including Research and Development planning, Alliance and Partnerships, Investment/Funding Strategy, and building a long-term Business Plan for the organization. CorriXR Therapeutics is a transformative research-based biotechnology company with a ground-breaking in-vivo gene editing therapeutic platform technology. Initial focus is on Oncology and specifically hard-to-treat solid… Show more Senior Executive Leader helping build an early stage biotechnology company. Focused on all key areas of company including Research and Development planning, Alliance and Partnerships, Investment/Funding Strategy, and building a long-term Business Plan for the organization. CorriXR Therapeutics is a transformative research-based biotechnology company with a ground-breaking in-vivo gene editing therapeutic platform technology. Initial focus is on Oncology and specifically hard-to-treat solid tumors starting with squamous cell carcinoma of the lung. The company is the initial biotech spin out of ChristianaCare’s Gene Editing Institute (GEI) where it was incubated for more than three years. ChristianaCare is a healthcare system in NorthEast Region of the U.S. that has also built and funded the Gene Editing Institute over the past seven years. CorriXR Therapeutics is uniquely positioned because of its relationship with ChristianaCare’s Gene Editing Institute and the Helen F. Graham Cancer Center and Research Institute which has collaborated with and guided GEI from its inception toward patient-centric therapy development. In addition, ChristianaCare, GEI, and CorriXR Therapeutics are very focused on bringing treatments and technologies to community-based patient populations through predominantly the work of female scientists and caregivers. Show less
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Member, Board of Directors
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Dec 2020 - Present
Hagerstown, Maryland, United States Board Member at an early-stage biopharmaceutical company initially targeting diseases impacted by the human microbiome.
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Diverse Biotech
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United States
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Biotechnology Research
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1 - 100 Employee
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Chief Executive Officer
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Sep 2019 - Dec 2021
Doylestown, PA Senior Executive Leader at a growing early stage Biopharma company with a novel advanced chemistry platform for new drug creation. The initial therapeutic focus was on Oncology and Rare Diseases, specifically Pancreatic Cancer, Glioblastoma, and Acute Flaccid Myelitis (AFM). Led a variety of key areas for the organization including Research and Development planning, Alliance and Partnerships, Investment/Funding Strategy, and building a long-term Business Plan for the organization. Was the… Show more Senior Executive Leader at a growing early stage Biopharma company with a novel advanced chemistry platform for new drug creation. The initial therapeutic focus was on Oncology and Rare Diseases, specifically Pancreatic Cancer, Glioblastoma, and Acute Flaccid Myelitis (AFM). Led a variety of key areas for the organization including Research and Development planning, Alliance and Partnerships, Investment/Funding Strategy, and building a long-term Business Plan for the organization. Was the Chief Commercial Officer until January 2021 and assumed the Chief Executive Officer role. Created significant value for the organization through orchestrating and finalizing a strategic transaction with Enveric Biosciences, a NASDAQ listed biotech company. Show less
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Principal
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Jan 2019 - Aug 2019
Princeton, NJ For an interim period after exiting Orexigen Therapeutics at the end of 2018, was an adviser and consultant to a number of small healthcare companies on their Commercial Development and go-to-market strategies. This included a varied group of companies in the BioPharma, Device, and Digital Health/Telemedicine spaces. Companies included Sesen Bio, electroCore, and DocTalkGo. Worked closely and specifically with CEOs in smaller organizations.
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Orexigen Therapeutics
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United States
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Pharmaceutical Manufacturing
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1 - 100 Employee
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Senior Vice President
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May 2016 - Dec 2018
La Jolla, California A Senior Leader in a small Biopharma company that went through a complete business model transformation. Focused on Commercial Development and Global Market Access, and involved in many different areas of the organization (Marketing, Sales, Supply Chain, Finance, Global Partnerships…etc.). Also helped to facilitate new innovative commercial business strategies including a TeleMedicine channel and Patient Home Delivery. Helped build a Commercial Team in the U.S. from the ground up… Show more A Senior Leader in a small Biopharma company that went through a complete business model transformation. Focused on Commercial Development and Global Market Access, and involved in many different areas of the organization (Marketing, Sales, Supply Chain, Finance, Global Partnerships…etc.). Also helped to facilitate new innovative commercial business strategies including a TeleMedicine channel and Patient Home Delivery. Helped build a Commercial Team in the U.S. from the ground up, going from <60 Global employees to >300 in less than 4 months. Took back the lead asset, Contrave for the treatment of Obesity, from Takeda in the U.S. and relaunched it in August 2016 with a completely new Commercial Team and approach. Annual revenue growth of >23% with less than 50% of the expense in comparison to Takeda. Company was sold to HighBridge Capital (a subsidiary of JP Morgan) and merged with pre-existing businesses. Show less
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Merck
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Managing Director, Global Health Innovation Investment Fund
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Sep 2015 - Apr 2016
White House Station, New Jersey U.S. Worked as a Managing Director in Merck’s Global Health Innovation Investment Fund. The group is Merck’s Venture Capital investment fund focused on healthcare technologies and adjacencies to core pharmaceutical business. Involved in learning the investment aspect of the fund, as well as a new role for Merck serving as an embedded Senior Leader or Executive-in-Residence to investment portfolio companies. Served as interim Chief Commercial Officer for a small start-up diagnostic company… Show more Worked as a Managing Director in Merck’s Global Health Innovation Investment Fund. The group is Merck’s Venture Capital investment fund focused on healthcare technologies and adjacencies to core pharmaceutical business. Involved in learning the investment aspect of the fund, as well as a new role for Merck serving as an embedded Senior Leader or Executive-in-Residence to investment portfolio companies. Served as interim Chief Commercial Officer for a small start-up diagnostic company in Cambridge, MA focused on new, innovative diagnostic technologies from Harvard University and M.I.T.
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Managing Director, Merck Sharp & Dohme (MSD) Ireland Human Health
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Dec 2012 - Aug 2015
Dublin, Ireland Managing Director of MSD's Human Health business, was responsible for the P&L of the Ireland subsidiary (i.e. directed, managed and controlled all operational activities of the subsidiary to ensure sustained growth in sales and profitability and continued competitive strength) through a strong focus on Business, Customers, & People. Essentially Chief Executive Officer (CEO) of Merck's Ireland Business. Elected member of the Strategy Board of the Irish Pharmaceutical Healthcare Association… Show more Managing Director of MSD's Human Health business, was responsible for the P&L of the Ireland subsidiary (i.e. directed, managed and controlled all operational activities of the subsidiary to ensure sustained growth in sales and profitability and continued competitive strength) through a strong focus on Business, Customers, & People. Essentially Chief Executive Officer (CEO) of Merck's Ireland Business. Elected member of the Strategy Board of the Irish Pharmaceutical Healthcare Association (IPHA) and Board Member of the American Chamber of Commerce Ireland (including Finance Committee).
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Vice President, West Commercial Operations Group
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Dec 2010 - Dec 2012
Responsible for a team of > 1,000 people as a distinct Business Unit within the U.S. responsible for more than $3B in annual Merck product sales. The group was made up of Sales, Account Management, Regional Marketing, and Business Planning functions and is focused mainly on Primary Care products (Allergy/Asthma, Cardiovascular, Diabetes, & Vaccines).
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Vice President, Managed Markets & Policy
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Nov 2009 - Dec 2010
Leader of a diverse team of > 75 people within the Managed Markets & Policy Business Unit consisting of multiple groups focused on Specialty Products & Business and the Hospital Business segment. Direct responsibility for developing and growing the entire broad new Merck product portfolio including Cardiovascular, Respiratory, Diabetes, CNS, Hepatitis/Virology, Oncology, Women's Health, and Vaccine products. Came over to the new Merck from Schering-Plough as a key leader in the U.S… Show more Leader of a diverse team of > 75 people within the Managed Markets & Policy Business Unit consisting of multiple groups focused on Specialty Products & Business and the Hospital Business segment. Direct responsibility for developing and growing the entire broad new Merck product portfolio including Cardiovascular, Respiratory, Diabetes, CNS, Hepatitis/Virology, Oncology, Women's Health, and Vaccine products. Came over to the new Merck from Schering-Plough as a key leader in the U.S. Marketplace.
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Merck
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Vice President, US Managed Markets – Healthcare Systems
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2008 - 2009
Oversaw a team of 10 Directors and > 100 Account Managers focused on partnering and promoting Schering-Plough (S-P) products to key customers in the core Healthcare Channel Segments in the US including HMOs, PBMs, VA/DoD, GPOs/Hospital Systems, State Medicaid Agencies, Medical Groups, and Specialty Pharmacies. Key Senior Leader responsible for all significant US Managed Markets strategies across 14 Core products, while working closely with Senior Sales and Marketing Leadership on overall US… Show more Oversaw a team of 10 Directors and > 100 Account Managers focused on partnering and promoting Schering-Plough (S-P) products to key customers in the core Healthcare Channel Segments in the US including HMOs, PBMs, VA/DoD, GPOs/Hospital Systems, State Medicaid Agencies, Medical Groups, and Specialty Pharmacies. Key Senior Leader responsible for all significant US Managed Markets strategies across 14 Core products, while working closely with Senior Sales and Marketing Leadership on overall US Brand Strategies.
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Executive Director, US Managed Markets, Geographic Business Group
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2005 - 2008
Led the US Managed Markets Geographic Business Group comprised of 6 Regional Directors and approximately 70 Account Managers with a focus on profitable formulary access, market share growth and customer integration / partnerships.
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Senior Director, Strategic Marketing Cardiovascular Disease & Hepatitis C
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2003 - 2005
Responsible for Strategic Marketing surrounding Cardiovascular and Hepatitis Product Franchises with particular emphasis on the Managed Markets arena.
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Director, Managed Care Marketing, Oncology / Biotech US
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2001 - 2003
Developed and implemented Managed Care Marketing Plan for the Hepatitis C and Oncology Product Franchises.
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Director, Gastroenterology / CNS Business Unit, Schering-Plough United Kingdom
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1999 - 2001
Held direct accountability for all Sales, Marketing, and Business Development activities for Gastroenterology/CNS Product lines in the United Kingdom. Started a new Business Unit in the UK subsidiary and more than doubled sales in 2 years.
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Merck
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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West Pacific District Sales Manager, Oncology / Biotech Business Unit
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1997 - 1998
Managed and motivated 14 Sales Representatives based in California, Nevada, and Hawaii calling on Oncologists, Hepatologists, Gastroenterologists, Urologists, & key accounts.
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Managed Care Account Mgr, US Managed Markets Business Unit
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1996 - 1997
National Account Manager for two of the largest Managed Care Organizations (MCOs) in the U.S.: United Healthcare & Aetna.
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Merck
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Additional Previous Roles......
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1989 - 1995
Sr. Mgr, Disease Mgmt / Managed Care Finance US Managed Markets Contracting Manager Marketing / Managed Care Research Analyst Professional Sales Representative
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Education
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The Wharton School
Bachelor of Science - BS, Economics -
University of Pennsylvania
Bachelor of Science - BS, Economics