Danny Chow

Associate Director, Quality Control at Fate Therapeutics Inc
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Contact Information
us****@****om
(386) 825-5501
Location
Irvine, California, United States, US
Languages
  • English Native or bilingual proficiency
  • Chinese Native or bilingual proficiency

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Experience

    • United States
    • Biotechnology Research
    • 200 - 300 Employee
    • Associate Director, Quality Control
      • Apr 2019 - Present

    • United States
    • Biotechnology Research
    • 700 & Above Employee
      • May 2018 - Mar 2019

      • Nov 2016 - Apr 2018

    • United States
    • Biotechnology
    • 200 - 300 Employee
    • Quality Control Analyst
      • May 2014 - Oct 2016

    • United States
    • Biotechnology Research
    • 700 & Above Employee
    • Scientist II
      • Dec 2012 - Mar 2014

      • Performed analytical testing for trace metal quantitation on ICP-MS of cell culture and raw material samples • Performed general maintenance of an Agilent 7500 ICP-MS instrument • Analyzed and quantified excipients, surfactants and raw materials using HPLC with different types of detectors (UV, CAD, RID) • Experienced in different types of chromatography (Reversed-Phase, Anion Exchange, Cation Exchange, Size Exclusion) • Established new methods for detecting different small molecules using LC-MS/MS • Improved the sensitivity and specificity of the existing analytical methods using an LC-MS/MS instrument • Operated a single quadrupole detector for the analysis of different small molecules • Performed ion chromatography and UV-Vis spectroscopy for detecting and quantitating different substances and molecules • Performed different types of extraction techniques in protein-containing samples (LLE, SPE, acid precipitation) Accomplishments: • Investigated the metal (Cu, Mn, Cr, and some other metals) impact with CHO cell growth • Developed a method on LCMS to detect multiple small molecules • Investigated the intra and extra cellular metal content for specific cell line in order to improve the cell growth • Improved different small molecule detection protocols (Time reduction, specificity, and detection limit) Show less

    • Staff Research Associate
      • Dec 2011 - Dec 2012

      Processed human serum sample that received over the clinical trial sites from all over the world, performed purification of the human serum sample, and operated LCMSMS for quantifying specific human hormone or substance. Key Responsibilities and results: •Performed liquid-liquid extraction for human serum samples •Optimized LCMSMS condition to quantify human hormone and specific drugs •Searched for specific signal for quantifying substance by using Mass Spectrophotometer •Analyzed the data generated from LCMSMS •Established new assay method for detecting new substance in LCMSMS Show less

    • Hong Kong
    • Higher Education
    • 700 & Above Employee
    • Research Assistant II
      • Jan 2009 - Jul 2011

      Performed immunology and virology related experiments for testing the effect of some siRNA, peptides, and drugs in vivo and vitro. Involved in specific protein (mouse beta defensin 4) induction and purification by using bacteria and insect cell as the expression host. Performed experiments in the Biohazard Level 3 Laboratory. Key Responsibilities and results: •Cultured different types of cells for experimental use and storage (Bacteria, MDCK, 293, Insect cell) •Tested the protective function of protein on the virus infection by using TCID50, Plaque Assay, and Hemagglutination test •Propagated different strains of virus (avian flu, swine flu, SARS, baculovirus) •Purified and identified different proteins by using SDS PAGE, FPLC, Western blot, and chromatography •Performed molecular biology related experiments (Molecular cloning, transformation, PCR) •Performed animal experiments such as injection, blood drawing, dissection, vaccination, organs extraction, animal breeding on mouse and rabbit •Successfully purified a small peptide (mouse beta-defensin and tested for the antiviral effect •Characterized physical and chemical properties of mouse beta-defensin 4 Show less

    • Chemical Trainee
      • Sep 2009 - Dec 2009

      Following the regulations of different countries, identify type of plastics using different type of technique and machine. Key Responsibilities: •Prepared chemical solutions for HPLC •Loaded some plastic samples onto GC-MS •Operated FTIP for identifying different plastics •Used flame test for identifying different plastics Following the regulations of different countries, identify type of plastics using different type of technique and machine. Key Responsibilities: •Prepared chemical solutions for HPLC •Loaded some plastic samples onto GC-MS •Operated FTIP for identifying different plastics •Used flame test for identifying different plastics

    • United States
    • Higher Education
    • 700 & Above Employee
    • Tutor
      • Sep 2005 - Mar 2006

      Tutoring student in the subject of mathematic, chemistry, and biology. Give them instruction on their homework. Key Responsibilities: Reviewed material from school (mathematic, chemistry, and biology) Helped the students on their upcoming exam Prepared the study note for students Tutoring student in the subject of mathematic, chemistry, and biology. Give them instruction on their homework. Key Responsibilities: Reviewed material from school (mathematic, chemistry, and biology) Helped the students on their upcoming exam Prepared the study note for students

Education

  • The Hong Kong University of Science and Technology
    Master of Science, Biotechnology
    2008 - 2010
  • UCLA
    Bachelor of Science, Physiological Science
    2006 - 2008

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