Experience

UC San Diego School of Medicine

• United States
• Higher Education
• 200 - 300 Employee

• Postdoc

  • Feb 2021 - Present



IGBMC

• Research Services
• 200 - 300 Employee

• Postdoc

  • Sep 2018 - Dec 2020

  - J. A. Louro*, R. Boopathi*, B. Beinsteiner, A. K. M. Patel, T. C. Cheng, D. Angelov, A. Hamiche, J. Bednar, S. Kale, B. Klaholz, S. Dimitrov (2023). "Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms". Structure. *Equal contribution (https://authors.elsevier.com/c/1gNY33SNvc2~At) - J. A. Louro*, R. Boopathi*, B. Beinsteiner, A. K. M. Patel, T. C. Cheng, D. Angelov, A. Hamiche, J. Bednar, S. Kale, B. Klaholz, S. Dimitrov (2023). "Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms". Structure. *Equal contribution (https://authors.elsevier.com/c/1gNY33SNvc2~At)



Centro de Investigaciones Biológicas Margarita Salas (CSIC)

• Biotechnology Research
• 100 - 200 Employee

• PhD Student

  • Sep 2011 - Sep 2017

  Dissertation: "Cryo-EM Structures of Free Monomeric and Rrn3-bound RNA Polymerase I Unveil the Structural Changes in the Transition from Inactive Dimers to the Activated State" As a PhD student I was able to learn: - Molecular cloning - Heterologous protein expression in E. coli and insect cells - Endogenous expression of a macromolecular complex from S. cerevisiae - Protein purification - In vitro reconstitution of a supramolecular protein complex - Sample preparation, data collection and image processing by negative-staining electron microscopy and cryo-electron microscopy (cryo-EM) - Pseudo-atomic model building of proteins (rigid-body real-space refinement) I have contributed to two published articles: - Torreira, E.*, J. A. Louro*, I. Pazos, N. González-Polo, D. Gil-Carton, A. G. Duran, S. Tosi, O. Gallego, O. Calvo and C. Fernández-Tornero (2017). "The dynamic assembly of distinct RNA polymerase I complexes modulates rDNA transcription." Elife 6. *Equal contribution - Garavís, M., N. González-Polo, P. Allepuz-Fuster, J. A. Louro, C. Fernández-Tornero, O. Calvo (2017). "Sub1 contacts the RNA polymerase II stalk to modulate mRNA synthesis." Nucleic Acids Res 45(5): 2458-2471. Show less



Biocant - Technology Transfer Association

• Portugal
• Biotechnology Research
• 1 - 100 Employee

• Research Fellow

  • Jul 2009 - Mar 2011



Farmácia S. Sebastião

• Coimbra, Portugal

• Community pharmacist

  • Sep 2008 - Mar 2009