Tomasz Benedyk
Virotherapy Scientist at EG 427- Claim this Profile
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Polish Native or bilingual proficiency
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English Full professional proficiency
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German Limited working proficiency
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Bio
Experience
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EG 427
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France
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Biotechnology Research
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1 - 100 Employee
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Virotherapy Scientist
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Mar 2022 - Present
Establishment and further development of a gene therapy platform based on non-replicative HSV-1 vectors. Introduction of advanced tools and strategies for vector design, engineering, research-scale production and quality control. Design of strategies for new producer cell lines generation, compliant with GMP standards. Establishment and further development of a gene therapy platform based on non-replicative HSV-1 vectors. Introduction of advanced tools and strategies for vector design, engineering, research-scale production and quality control. Design of strategies for new producer cell lines generation, compliant with GMP standards.
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University of Cambridge
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United Kingdom
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Research Services
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700 & Above Employee
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Researcher - PhD Candidate
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Jan 2018 - Feb 2022
Investigation of protein interactions at near-atomic resolution during herpesvirus infection in human host. With particular interest in flexible, intrinsically disordered and post-translationally modified systems. Elucidation of viral protein functions with (phospho)proteomic screenings and studying their role in host lipid homeostasis using small-molecule labeling and HPTLC. My two first-authored manuscripts provide mechanistic and biochemical insights into the novel viral phosphatase adaptor HSV-1 pUL21. The studies explain its role in viral replication and dissemination, and highlights its strong potential for a new druggable target. Show less
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Polygeia
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United Kingdom
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Think Tanks
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1 - 100 Employee
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Editor
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Jan 2018 - Dec 2020
Evaluation of public access to surgical care in the Philippines.
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Marketing and Sponsorship Advisor
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Jan 2019 - Nov 2019
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Federation of European Microbiological Societies
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Netherlands
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Non-profit Organizations
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1 - 100 Employee
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Blogger in One Health Campaign
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Mar 2016 - Mar 2019
Writing blog posts addressing emerging zoonotic diseases and multidrug resistent pathogens. Writing blog posts addressing emerging zoonotic diseases and multidrug resistent pathogens.
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University of Helsinki
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Finland
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Higher Education
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700 & Above Employee
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Laboratory Researcher
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Jan 2015 - Dec 2017
In my work, I was focused on genetics of different virulence factors of Yersinia entercolitica. I investigated the interplay between metabolic states of Y. enterocolitica and the organisation of its outer membrane structures, based of the RNAseq data and using publicly available bioinformatic tools.
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Researcher at Translational Cancer Research Program - Viral Tumorigenesis
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Jan 2017 - Sep 2017
My goal was to understand the role of certain human proteins in viral defence and to explore how the virus hijacks their primary functions. Another area of my research included generating new in vitro platforms to improve and facilitate the control over KSHV genes expression system.
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The University of Edinburgh
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United Kingdom
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Research Services
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700 & Above Employee
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Visiting Researcher
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Jul 2016 - Nov 2016
Title of the project: "Tracking of the Heligmosomoides polygyrus excretory-secretory products using biologically and functionally inert labelling of enodgenous biomolecules." The ultimate goal of my work was to optimize the methods of tracking the content, RNA and protein in particular, of EVs using a technique of biological molecules labelling called ‘Click Chemistry’. Title of the project: "Tracking of the Heligmosomoides polygyrus excretory-secretory products using biologically and functionally inert labelling of enodgenous biomolecules." The ultimate goal of my work was to optimize the methods of tracking the content, RNA and protein in particular, of EVs using a technique of biological molecules labelling called ‘Click Chemistry’.
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voestalpine
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Austria
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Mining
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700 & Above Employee
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Summer Intern
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Sep 2014 - Sep 2014
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SABMiller
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Food & Beverages
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700 & Above Employee
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Research Intern
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Jan 2014 - Jun 2014
Carrying out an industrial-scaled research project titled: "The alcohol fermentation’s by-products of Saccharomyces cerevisiae, with a particular emphasis on the formation and reduction of diacetyl" Carrying out an industrial-scaled research project titled: "The alcohol fermentation’s by-products of Saccharomyces cerevisiae, with a particular emphasis on the formation and reduction of diacetyl"
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Education
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University of Cambridge
Doctor of Philosophy - PhD, Pathology/Virology -
University of Helsinki
Master of Science (M.S.), Translational Medicine -
Uniwersytet Wrocławski
Bachelor of Science (B.S.), Biotechnology