Alexander Jacobine
Senior Manager, Process Chemistry at Blueprint Medicines- Claim this Profile
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Bio
Jeremy Kintigh, PhD
I worked with Dr. Jacobine while a teaching assistant at the University of New Hampshire. Alex was a tremendous help in setting up the lab, teaching the students, and grading. During this time in teaching Alex was also able to make consistent progress in graduate research, winning a number of awards, and presenting his work at national meetings. Alex has great expertise in organic synthesis and is able to produce reliable, consistent results. I would highly recommended him for either an academic or industrial position.
Christopher Hencken
Alex and I worked together in the Posner group at Johns Hopkins for over a year. As a post-doctoral research associate, his knowledge of organic/medicinal chemistry and experimental techniques were very good. He worked on the malaria drug discovery project where he made several significant contributions. He also worked on the selenium method project that led to his J. Org. Chem. publication on rhodanines. Alex was a friendly coworker and a valuable asset to our research group and his communication and organizational skills, work ethic, and his creative problem-solving abilities made Alex a pleasure to work with.
Jeremy Kintigh, PhD
I worked with Dr. Jacobine while a teaching assistant at the University of New Hampshire. Alex was a tremendous help in setting up the lab, teaching the students, and grading. During this time in teaching Alex was also able to make consistent progress in graduate research, winning a number of awards, and presenting his work at national meetings. Alex has great expertise in organic synthesis and is able to produce reliable, consistent results. I would highly recommended him for either an academic or industrial position.
Christopher Hencken
Alex and I worked together in the Posner group at Johns Hopkins for over a year. As a post-doctoral research associate, his knowledge of organic/medicinal chemistry and experimental techniques were very good. He worked on the malaria drug discovery project where he made several significant contributions. He also worked on the selenium method project that led to his J. Org. Chem. publication on rhodanines. Alex was a friendly coworker and a valuable asset to our research group and his communication and organizational skills, work ethic, and his creative problem-solving abilities made Alex a pleasure to work with.
Jeremy Kintigh, PhD
I worked with Dr. Jacobine while a teaching assistant at the University of New Hampshire. Alex was a tremendous help in setting up the lab, teaching the students, and grading. During this time in teaching Alex was also able to make consistent progress in graduate research, winning a number of awards, and presenting his work at national meetings. Alex has great expertise in organic synthesis and is able to produce reliable, consistent results. I would highly recommended him for either an academic or industrial position.
Christopher Hencken
Alex and I worked together in the Posner group at Johns Hopkins for over a year. As a post-doctoral research associate, his knowledge of organic/medicinal chemistry and experimental techniques were very good. He worked on the malaria drug discovery project where he made several significant contributions. He also worked on the selenium method project that led to his J. Org. Chem. publication on rhodanines. Alex was a friendly coworker and a valuable asset to our research group and his communication and organizational skills, work ethic, and his creative problem-solving abilities made Alex a pleasure to work with.
Jeremy Kintigh, PhD
I worked with Dr. Jacobine while a teaching assistant at the University of New Hampshire. Alex was a tremendous help in setting up the lab, teaching the students, and grading. During this time in teaching Alex was also able to make consistent progress in graduate research, winning a number of awards, and presenting his work at national meetings. Alex has great expertise in organic synthesis and is able to produce reliable, consistent results. I would highly recommended him for either an academic or industrial position.
Christopher Hencken
Alex and I worked together in the Posner group at Johns Hopkins for over a year. As a post-doctoral research associate, his knowledge of organic/medicinal chemistry and experimental techniques were very good. He worked on the malaria drug discovery project where he made several significant contributions. He also worked on the selenium method project that led to his J. Org. Chem. publication on rhodanines. Alex was a friendly coworker and a valuable asset to our research group and his communication and organizational skills, work ethic, and his creative problem-solving abilities made Alex a pleasure to work with.
Credentials
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From the Laboratory to Leadership
The Leadership EdgeApr, 2023- Nov, 2024
Experience
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Blueprint Medicines
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United States
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Biotechnology Research
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400 - 500 Employee
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Senior Manager, Process Chemistry
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Jun 2020 - Present
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Alkermes
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Ireland
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Biotechnology Research
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700 & Above Employee
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Senior Scientist
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Mar 2019 - Jun 2020
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Scientist
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Oct 2017 - Mar 2019
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Johnson Matthey
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United Kingdom
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Chemical Manufacturing
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700 & Above Employee
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Scientist
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Apr 2015 - Oct 2017
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Merck
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Postdoctoral Research Fellow
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Mar 2013 - Apr 2015
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The Johns Hopkins University
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United States
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Higher Education
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700 & Above Employee
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Post-Doctoral Researcher
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Jun 2010 - Mar 2013
Advisor: Professor Gary H. Posner -Synthetic methodology project focused on a three component, one flask, sequential construction of a series of aliphatic rhodanine derivatives -Design and synthesis of artemisinin-derived, antimalarial drug candidates for in vivo and in vitro testing on milligram scale Advisor: Professor Gary H. Posner -Synthetic methodology project focused on a three component, one flask, sequential construction of a series of aliphatic rhodanine derivatives -Design and synthesis of artemisinin-derived, antimalarial drug candidates for in vivo and in vitro testing on milligram scale
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University of New Hampshire
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United States
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Higher Education
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700 & Above Employee
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Graduate Student
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Aug 2005 - Jun 2010
Advisor: Professor Charles K. Zercher -Organozinc synthetic methodology towards oxygen and nitrogen heterocycles -Synthesis of β-proline derivatives and other amino acid substrates -Synthetic methodology project focused around an unprecedented oxidation of hemiketals to gain access to a family of naturally occurring γ-lactones known as paraconic acids. Additionally, one diastereomer of phaseolinic acid was synthesized in the shortest sequence reported in the literature. Advisor: Professor Charles K. Zercher -Organozinc synthetic methodology towards oxygen and nitrogen heterocycles -Synthesis of β-proline derivatives and other amino acid substrates -Synthetic methodology project focused around an unprecedented oxidation of hemiketals to gain access to a family of naturally occurring γ-lactones known as paraconic acids. Additionally, one diastereomer of phaseolinic acid was synthesized in the shortest sequence reported in the literature.
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Washington College
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United States
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Higher Education
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400 - 500 Employee
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Undergraduate Student
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Aug 2001 - May 2005
Advisor: Professor Frank J. Creegan -Baeyer-Villiger oxidations on a series of substituted indanones to investigate the regioselectivity of the reaction based on observed products -Products were characterized by GC/MS and compared to known standards Advisor: Professor Frank J. Creegan -Baeyer-Villiger oxidations on a series of substituted indanones to investigate the regioselectivity of the reaction based on observed products -Products were characterized by GC/MS and compared to known standards
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Summer Intern
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2002 - 2005
I worked in the pilot plant on scale-up and packaging for one summer as an intern. I also was a summer intern for three years in the R&D labs working on formulations, coating, and testing of physical properties. I worked in the pilot plant on scale-up and packaging for one summer as an intern. I also was a summer intern for three years in the R&D labs working on formulations, coating, and testing of physical properties.
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Education
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2005 - 2010
University of New Hampshire
Ph. D., Chemistry -
2001 - 2005
Washington College
B.S., Chemistry -
1997 - 2001
Francis T. Maloney High School
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