Evgeny Altshuler

Scientific Researcher at HyTest
  • Claim this Profile
Contact Information
us****@****om
(386) 825-5501
Location
Turku, Southwest Finland, Finland, FI
Languages
  • Russian Native or bilingual proficiency
  • English Professional working proficiency
  • Spanish Professional working proficiency
  • German Elementary proficiency
Skills

Topline Score

Topline score feature will be out soon.

Bio

Generated by
Topline AI

You need to have a working account to view this content.
Join now
You need to have a working account to view this content.
Join now

Credentials

  • Algorithms: Design and Analysis, Part 1
    Coursera
    Dec, 2014
    - Oct, 2024
  • Bioinformatics Algorithms (Part 1)
    Coursera
    Feb, 2014
    - Oct, 2024

Experience

  • HyTest
    • Finland
    • Biotechnology Research
    • 1 - 100 Employee
    • Scientific Researcher
      • Dec 2022 - Present

      Responsibilities: - multiple scripts and macros for optimising daily routines and procedures - affinity maturation of recombinant Mabs - internal data analysis pipeline development (4PL curve fitting and reverse prediction, kinetic constant calculation, absorbtion spectra prediction, alignment handling tools, local Mab DB analysis tools, primer design for antibody sequencing and humanization) - user-friendly interface to the pipeline web-services (Flask/React)

    • Scientific Researcher
      • Apr 2018 - Nov 2022

      At HyTest, we manufacture monoclonal antibodies and antigens that are mainly used as key components of laboratory tests. Our company is one of the most important raw material suppliers for the IVD industry. Responsibilities: - recombinant protein expression, purification, characterisation - affinity maturation of recombinant Mabs - stability study, QC - characterisation of new antibodies (kinetics, different antigens, assay setups, pairs) - internal data analysis pipeline… Show more At HyTest, we manufacture monoclonal antibodies and antigens that are mainly used as key components of laboratory tests. Our company is one of the most important raw material suppliers for the IVD industry. Responsibilities: - recombinant protein expression, purification, characterisation - affinity maturation of recombinant Mabs - stability study, QC - characterisation of new antibodies (kinetics, different antigens, assay setups, pairs) - internal data analysis pipeline development (4PL curve fitting and reverse prediction, kinetic constant calculation, absorbtion spectra prediction, alignment handling tools, local Mab DB analysis tools, primer design for antibody sequencing and humanization) - user-friendly interface to the pipeline web-services (Flask/Shiny) - multiple scripts and macros for optimising daily routines and procedures

  • Lomonosov Moscow State University (MSU)
    • Higher Education
    • 300 - 400 Employee
    • Scientific Researcher
      • 2013 - Nov 2023

      Research: - Cardiac marker studies using a panel of specific antibodies - Generation and optimisation of recombinant antibody fragments Gene engineering practical course: - molecular cloning (bacterial cultures, minipreps, PCR, restriction, ligation, transformation) - mutagenesis - creating chimeras - recombinant protein production optimisation - protein extraction, quantification and visualisation (lysis, PAGE, WB) - report preparation Biostatistics course… Show more Research: - Cardiac marker studies using a panel of specific antibodies - Generation and optimisation of recombinant antibody fragments Gene engineering practical course: - molecular cloning (bacterial cultures, minipreps, PCR, restriction, ligation, transformation) - mutagenesis - creating chimeras - recombinant protein production optimisation - protein extraction, quantification and visualisation (lysis, PAGE, WB) - report preparation Biostatistics course for biochemistry students using R: - R language basics and data structures - basic statistics (mean, median, sd, var, cor) - data manipulation - tidy data manipulation - import/export - plotting with ggplot (scatterplots, histograms, boxplots, qqplots, custom plots) - normality checks and (non)parametric methods, hypothesis testing, sample size and effect size - data simulation and bootstrap - linear and non-linear regression, differential equations, curve fitting, calibration curves, anova Other responsibilities: - Generation, content management and support of the Biochemistry Department web page. Show less Research: - Cardiac marker studies using a panel of specific antibodies - Generation and optimisation of recombinant antibody fragments Gene engineering practical course: - molecular cloning (bacterial cultures, minipreps, PCR, restriction, ligation, transformation) - mutagenesis - creating chimeras - recombinant protein production optimisation - protein extraction, quantification and visualisation (lysis, PAGE, WB) - report preparation Biostatistics course… Show more Research: - Cardiac marker studies using a panel of specific antibodies - Generation and optimisation of recombinant antibody fragments Gene engineering practical course: - molecular cloning (bacterial cultures, minipreps, PCR, restriction, ligation, transformation) - mutagenesis - creating chimeras - recombinant protein production optimisation - protein extraction, quantification and visualisation (lysis, PAGE, WB) - report preparation Biostatistics course for biochemistry students using R: - R language basics and data structures - basic statistics (mean, median, sd, var, cor) - data manipulation - tidy data manipulation - import/export - plotting with ggplot (scatterplots, histograms, boxplots, qqplots, custom plots) - normality checks and (non)parametric methods, hypothesis testing, sample size and effect size - data simulation and bootstrap - linear and non-linear regression, differential equations, curve fitting, calibration curves, anova Other responsibilities: - Generation, content management and support of the Biochemistry Department web page. Show less

  • Moscow South-West High School #1543
    • Moscow, Moscow City, Russia
    • Biology Teacher
      • Sep 2013 - Dec 2022

      Special course of biochemistry for the students of the biology track - intro to biochemistry - molecules of life, their hierarchy - water as a solvent, electrolytes, buffers - what thermodynamics and kinetics can tell us about chemical reactions - metabolism, principles for regulation - carbohydrates: structure, functions, reactions, diversity, metabolism - lipids: structure, functions, reactions, diversity, metabolism - proteins: structure, functions, reactions… Show more Special course of biochemistry for the students of the biology track - intro to biochemistry - molecules of life, their hierarchy - water as a solvent, electrolytes, buffers - what thermodynamics and kinetics can tell us about chemical reactions - metabolism, principles for regulation - carbohydrates: structure, functions, reactions, diversity, metabolism - lipids: structure, functions, reactions, diversity, metabolism - proteins: structure, functions, reactions, diversity, metabolism - enzymatic catalysis Show less Special course of biochemistry for the students of the biology track - intro to biochemistry - molecules of life, their hierarchy - water as a solvent, electrolytes, buffers - what thermodynamics and kinetics can tell us about chemical reactions - metabolism, principles for regulation - carbohydrates: structure, functions, reactions, diversity, metabolism - lipids: structure, functions, reactions, diversity, metabolism - proteins: structure, functions, reactions… Show more Special course of biochemistry for the students of the biology track - intro to biochemistry - molecules of life, their hierarchy - water as a solvent, electrolytes, buffers - what thermodynamics and kinetics can tell us about chemical reactions - metabolism, principles for regulation - carbohydrates: structure, functions, reactions, diversity, metabolism - lipids: structure, functions, reactions, diversity, metabolism - proteins: structure, functions, reactions, diversity, metabolism - enzymatic catalysis Show less

  • LLC Bialexa
    • Moscow, Moscow City, Russia
    • Scientific Researcher
      • 2010 - Apr 2018

      Responsibilities - recombinant protein expression and purification - protein stability analysis and QC - protein biochemical and immunochemical properties - characterisation of new antibodies (kinetics, different antigens, assay setups, pairs) - development of a pipeline for developing degenerate primer sets for new antibody sequencing - development of a pipeline for animal antibody humanisation - multiple scripts and macros for optimising daily routines and procedures Responsibilities - recombinant protein expression and purification - protein stability analysis and QC - protein biochemical and immunochemical properties - characterisation of new antibodies (kinetics, different antigens, assay setups, pairs) - development of a pipeline for developing degenerate primer sets for new antibody sequencing - development of a pipeline for animal antibody humanisation - multiple scripts and macros for optimising daily routines and procedures

  • Remote Teaching Center for Supplementary Education
    • Moscow, Moscow City, Russia
    • Web Developer
      • May 2005 - Mar 2008

      Responsibilities - created web interfaces for command line linux-based user management platform - web portal engine updates, tech support and troubleshooting - technical support for talented children school conferences Responsibilities - created web interfaces for command line linux-based user management platform - web portal engine updates, tech support and troubleshooting - technical support for talented children school conferences

  • Lomonosov Moscow State University (MSU)
    • Higher Education
    • 300 - 400 Employee
    • Software Developer
      • Aug 2007 - Feb 2008

      Plant genosystematics lab Created custom phylogenetic tree manipulation and analysis tool - bootstrapping, fragment generation and concatenation of alignments - compare different trees by custom metrics and visualise results Plant genosystematics lab Created custom phylogenetic tree manipulation and analysis tool - bootstrapping, fragment generation and concatenation of alignments - compare different trees by custom metrics and visualise results

  • Sodis Travel Company
    • Russian Federation
    • Travel Arrangements
    • Web Developer
      • Nov 2006 - Apr 2007

      Responsibilities: Developed a Drupal module for internal web-portal to manage lunch menu for company staff. It allows portal users to select items from the menu within defined time limits and managers to add/remove/edit items and control payment status. Responsibilities: Developed a Drupal module for internal web-portal to manage lunch menu for company staff. It allows portal users to select items from the menu within defined time limits and managers to add/remove/edit items and control payment status.

Education

  • Lomonosov Moscow State University (MSU)
    Doctor of Philosophy (PhD), Biochemstry
    2009 - 2012
  • Lomonosov Moscow State University (MSU)
    Specialist, Biochemistry
    2004 - 2009
  • Moscow South-West High School #1543
    Biology
    2000 - 2004
  • Moscow School 820
    1994 - 2000

Community

You need to have a working account to view this content. Click here to join now