Jordi Silvestre-Ryan

Scientist at Atomwise
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Contact Information
us****@****om
(386) 825-5501
Location
San Francisco, California, United States, US

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Bio

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Scientist
      • Sep 2022 - Present

      Developing and validating deep learning models to accelerate drug discovery. Developing and validating deep learning models to accelerate drug discovery.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Graduate Student
      • May 2016 - Dec 2022

      Built machine learning methods for consensus and basecalling of nanopore sequencing data. Developed an algorithm to find a consensus sequence from two complementary reads, which halved the error rate and was adopted into the official Oxford Nanopore basecaller. Built machine learning methods for consensus and basecalling of nanopore sequencing data. Developed an algorithm to find a consensus sequence from two complementary reads, which halved the error rate and was adopted into the official Oxford Nanopore basecaller.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Graduate Student
      • Sep 2012 - Dec 2015

      Probed transcriptional feedback loops using deterministic and stochastic models of gene regulatory networks. Applied techniques in experimental cell biology to explore epigenetic cellular memory in Candida albicans. Probed transcriptional feedback loops using deterministic and stochastic models of gene regulatory networks. Applied techniques in experimental cell biology to explore epigenetic cellular memory in Candida albicans.

    • Spain
    • Research Services
    • 300 - 400 Employee
    • Research Assistant
      • Jun 2011 - Jun 2012

      Validated a Monte Carlo approach for fitting protein structure ensembles to data from biophysical experiments (NMR and small angle X-ray scattering). Applied method to reveal novel interactions in a protein implicated in neurodegenerative disease. Validated a Monte Carlo approach for fitting protein structure ensembles to data from biophysical experiments (NMR and small angle X-ray scattering). Applied method to reveal novel interactions in a protein implicated in neurodegenerative disease.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Research Assistant
      • Jan 2009 - May 2011

      Implemented bioinformatics pipeline to look for groups of co-evolving amino acids in proteins. Integrated bioinformatics with molecular simulation to examine enzyme conformational change. Implemented bioinformatics pipeline to look for groups of co-evolving amino acids in proteins. Integrated bioinformatics with molecular simulation to examine enzyme conformational change.

Education

  • UC Berkeley-UCSF Graduate Program in Bioengineering
    Doctor of Philosophy (PhD), Bioengineering
    2016 - 2022
  • University of California, San Francisco
    Master of Science (MS), Biophysics
    2012 - 2015
  • University of California, Berkeley
    Bachelor of Science (BS), Bioengineering
    2007 - 2011

Community

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