MSAT Associate Scientist II

• Jun 2023 - Present

MSAT Associate Scientist I

• Apr 2022 - Jun 2023

Research Scientist

• Aug 2021 - Mar 2022

• Piloted yeast engineering project. • Designed and executed molecular biology experiments. • Technical knowledge acquired: CRISPR-Cas gene editing, 3rd-Generation sequencing, RT-qPCR. • Piloted yeast engineering project. • Designed and executed molecular biology experiments. • Technical knowledge acquired: CRISPR-Cas gene editing, 3rd-Generation sequencing, RT-qPCR.

Research Associate, Microbiologist

• Aug 2020 - Jun 2021

• Closely worked with material scientist and chemist, directly reported to Chief-Scientific-Officer. • Developed analytical SOPs. • Piloted microbial tests of next-generation functional coatings. • Conducted biochemical assays, obtained data on efficacy and storage stability of pipeline novel drug delivery product. • Developed cytotoxicity experiment of MRC-5 cell line. • Participated in designing pre-clinical trials for pipeline drug delivery product. • Collaborated with technical team to create regulatory documents. • Collaborated with business team to conduct marketing research. • Technical knowledge acquired: Confocal Microscopy, HPLC/LCMSMS data analysis, Preparation of Regulatory documents. Show less

Postdoctoral Fellow

• Oct 2015 - Jul 2019

I independently lead the project aims to understand the evolution of host-pathogen interactions. The human pathogen Legionella pneumophila maintains the largest arsenal of effectors among all bacterial pathogens, with over 330 effector proteins translocated by translocation system. My specific focus in this project was to answer the question of how L. pneumophila was able to acquire and maintain such a large arsenal of effectors using a unique experimental evolution method that represents an exciting new direction for gene evolution modelling. • Initiated and piloted the research project supported by NSERC Discovery Grant. • Designed and conducted molecular biology and biochemistry experiment to understand the evolution of host-pathogen interactions. • Independently developed a unique experimental evolution method that represents an exciting new direction for gene evolution modelling. • Initiated and established the collaboration with other researchers from other universities such as Johns Hopkins University School of Medicine. • Mentored 4 students including Masters and PhDs in their research projects. • Technical knowledge acquired: Cell culturing, Infectious Disease, human-pathogen interaction, Next-Generation Sequencing (NGS), Immunofluorescence, SAS Certified Base Programmer, SQL, Python. Show less

Graduate Research Assistant

• Sep 2010 - Jul 2015

• Initiated and completed the research project on adaptation of bacteria to redox-stratified environment in a newly established lab. • Supervised 6 undergrads in conducting experiments, gathering data, and analyzing results to obtain valuable conclusions. • Teaching Assistant in microbiology experiment course for 2 semesters. In charge of demonstrating research techniques and organizing review sessions. • Authored 6 scientific papers on peer-reviewed journal. • Technical knowledge acquired: PCR, DNA/Protein Purification, Cloning, Anaerobic culture, Western Blotting, ELISA, Immunofluorescence, Molecular biology, Microbiology, Biotechnology, Biochemistry, Good Lab Practice, Biosafety. Show less