Bioinformatics System Software Engineer II

• Sep 2022 - Present

Associate Bioinformatics Programmer

• Feb 2022 - Aug 2022

1. Develop sequencing analysis pipelines for a new chromatin profiling assay, CUT&RUN, to generate high-resolution footprints of transcription factor binding sites under Linux environment 2. Collaborate with lab scientists to integrate our in-house machine learning program on the single-cell NGS analysis pipeline, scATAC-seq, and improve the chromatin accessibility results 3. Facilitate our epigenetic study workflow by standardizing NGS processing pipelines, managing data storage and documentation, and providing data analysis support for lab scientists with Python (Pandas, Matplotlib) 4. Work under Linux and HPC (Slurm) environment to utilize bioinformatics tools, schedule multiple analysis tasks, and coordinate data transfer with our external collaborators Show less

Computational Biology Intern

• Aug 2021 - Jan 2022

Research Focus: Reconstructing gene regulatory network (GRN) for cardiovascular tissue 1. Implemented a Java-based program to compute gene-gene correlation with RNA-seq results and reconstruct gene regulatory network (GRN) in cardiovascular tissues 2. Developed pipelines with Python and R to perform upstream processing for GRN analysis Research Focus: Reconstructing gene regulatory network (GRN) for cardiovascular tissue 1. Implemented a Java-based program to compute gene-gene correlation with RNA-seq results and reconstruct gene regulatory network (GRN) in cardiovascular tissues 2. Developed pipelines with Python and R to perform upstream processing for GRN analysis

Business Operation Intern

• Sep 2020 - Dec 2020

1. Cooperated with senior engineers to create detailed manufacturing manuals for 3 different products 2. Delivered product demonstration and technical support for our Western Blots imaging system to customers 1. Cooperated with senior engineers to create detailed manufacturing manuals for 3 different products 2. Delivered product demonstration and technical support for our Western Blots imaging system to customers

Lab Prep Graduate Assistant

• Sep 2019 - May 2020

• Prepared experimental materials for a 150-student class by tracking inventory, making chemical reagents, setting up equipment, and testing experiments in advance • Provided immediate equipment repairing, material replenishing, and hazard removing to maintain an effective learning environment and facilitate the course progress • Prepared experimental materials for a 150-student class by tracking inventory, making chemical reagents, setting up equipment, and testing experiments in advance • Provided immediate equipment repairing, material replenishing, and hazard removing to maintain an effective learning environment and facilitate the course progress

Undergraduate Research Fellow

• Jul 2018 - Feb 2019

• Awarded with College Student Research Scholarship from Ministry of Science and Technology • Conducted independent research and wrote a research paper about the critical role of Hal4 and Hal5 protein kinases in autophagy machinery • Analyzed DNA sequencing data with computational tools to examine the quality of DNA cloning results • Proficient in commonly used lab techniques such as PCR, electrophoresis, Western blot, DNA sequencing, and microbial culture methods • Organized monthly journal club meetings to increase exposure to the latest scientific discoveries and exchange insight on each member’s research progress Show less