Pauline Carlotta Göller

Senior Scientist at Clemedi
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Contact Information
us****@****om
(386) 825-5501
Location
Zurich, Zurich, Switzerland, CH
Languages
  • German Native or bilingual proficiency
  • English Native or bilingual proficiency
  • French Professional working proficiency
  • Swedish Elementary proficiency

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Experience

    • Switzerland
    • Medical Device
    • 1 - 100 Employee
    • Senior Scientist
      • Oct 2021 - Present

      • Scientific leadership for in vitro diagnostic product development in biotech startup for antibiotic resistance prediction in M. tuberculosis infections using next generation sequencing technology and AI• Implemented wet-lab documentation under ISO13485. Wrote method documents, user manuals and analytical performance test plans for in vitro diagnostic directive (IVDD) 98/79/EG. • Planned and conducted wet-lab validation experiments for targeted NGS IVDD product registration • Scientific leadership for in vitro diagnostic product development in biotech startup for antibiotic resistance prediction in M. tuberculosis infections using next generation sequencing technology and AI• Implemented wet-lab documentation under ISO13485. Wrote method documents, user manuals and analytical performance test plans for in vitro diagnostic directive (IVDD) 98/79/EG. • Planned and conducted wet-lab validation experiments for targeted NGS IVDD product registration

    • Switzerland
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Scientist
      • Oct 2021 - Present

      • Research on innovative diagnostic solutions in the field of mycobacteriology.• Successful coordination of multiple, simultaneous projects, including multinational technical evaluation studies on novel diagnostic tests. Designed clinical study protocols, coordinated study partners, and managed data acquisition (RedCap). Met project goals on time and budget.• Implemented targeted Oxford Nanopore sequencing for therapeutic guidance for drug resistant M. tuberculosis infections in low and middle income countries.• Managed three third party research funds. Supervised lab technicians.

    • Switzerland
    • Higher Education
    • 700 & Above Employee
    • Ph.D. Graduate Student
      • Aug 2017 - Jun 2021

      • Research on prokaryotic viruses and their host interactions in the context of antimicrobial gene transmissions using both functional and sequenced based metagenomics.• Isolated, purified and characterized novel virus isolates (N=100) and viral communities (soil, wastewater). Established viral DNA extraction protocols prior long- and short read next generation sequencing. Cultured database with >10’000 host viral interactions and designed wetlab protocols to record gene transmissions. Implemented bioinformatic pipelines for viral genomics and the in silico detection of antibiotic resistance.• Organized and condensed large data samples and applied a wide range of statistical analyses.• Lead and managed 8 (post)graduate students from onboarding to performance management.• Wrote first author publications for two high impact journals.• Effective and autonomous time and project management

    • Spain
    • Higher Education
    • 700 & Above Employee
    • Research Intern
      • Oct 2018 - Dec 2018

      • Research and bioinformatic training in viral genomics.• Collaborative research and bioinformatic training in predicting antibiotic resistance genes in viral communities. • Research and bioinformatic training in viral genomics.• Collaborative research and bioinformatic training in predicting antibiotic resistance genes in viral communities.

    • Research Services
    • 700 & Above Employee
    • Graduate Researcher
      • Jan 2016 - Jun 2016

      • M. sc. thesis in neuronal gene therapy using lentiviral vectors. • Designed and produced lentiviral vectors to establish an in vitro model of Parkinson’s Disease and to assess lentiviral mediated neuroprotection using heat-shock proteins.• Master thesis awarded with Distinction • M. sc. thesis in neuronal gene therapy using lentiviral vectors. • Designed and produced lentiviral vectors to establish an in vitro model of Parkinson’s Disease and to assess lentiviral mediated neuroprotection using heat-shock proteins.• Master thesis awarded with Distinction

    • Switzerland
    • Higher Education
    • 700 & Above Employee
    • Tutor in Histology for Medical Students
      • Sep 2014 - Jun 2015

      • Tutored medical students in french and german on patho-histological specimens • Tutored medical students in french and german on patho-histological specimens

Education

  • ETH Zürich
    Dr. sc., Microbiology and Immunology
    2017 - 2021
  • Imperial College London
    M.Sc. in Pathology and Molecular Biology of Viruses, Faculty of Medicine
    2015 - 2016
  • Université de Fribourg - Universität Freiburg
    Bilingual (French and German) B.Sc., Medical Clinical Sciences/Graduate Medical Studies
    2012 - 2015
  • Kantonale Mittelschule Uri
    Secondary Education, Physics and Applied Mathematics
    -

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