Experience

Axxam

• Italy
• Biotechnology Research
• 100 - 200 Employee

• Head of Discovery Chemistry

  • Jun 2023 - Present

  As head of Discovery Chemistry I am leading the Medicinal Chemistry and the compound Management Units • Design and execution of Discovery Chemistry Strategies • Drug Discovery research consultancy • Team management • Business development and operational strategy As head of Discovery Chemistry I am leading the Medicinal Chemistry and the compound Management Units • Design and execution of Discovery Chemistry Strategies • Drug Discovery research consultancy • Team management • Business development and operational strategy



Università di Pisa

• Higher Education
• 700 & Above Employee

• Academic Advisory Board

  • Dec 2020 - Present

  The committee gives suggestions and advice on how to modify the Master degree course to bring it closer to professional needs. As member of the board: • Once a year I hold a career-focused seminar • I keep an active loop between academia and industry The committee gives suggestions and advice on how to modify the Master degree course to bring it closer to professional needs. As member of the board: • Once a year I hold a career-focused seminar • I keep an active loop between academia and industry



TeamC - The EArly Medicinal Chemistry Consulting

• Copenhagen, Capital Region, Denmark

• Founder & Director

  • Feb 2023 - Jun 2023



Scandion Oncology

• Denmark
• Biotechnology Research
• 1 - 100 Employee

• Director of Medicinal Chemistry

  • Aug 2022 - Jan 2023

  As Director of Medicinal Chemistry att Scandion Oncology, a clinical biotech working in cancer drug resistance, I am responsible for building an early-stage platform with the goal of identifying new back up molecules for the existing clinical and pre-clinical assets and to evaluate new approaches to tackle cancer drug resistance. • Deep data analysis of the current pre-clinical programs • Design of new analogues, definition of screening cascades, implementation of collaborations with CROs and management of interdisciplinary activities. • Key role in the generation of a data package and in accelerating the decision-making process for the follow-up activities of our advanced pre-clinical candidate. Show less



Vipergen ApS

• Denmark
• Biotechnology Research
• 1 - 100 Employee

• Associate Director of Chemistry and Alliances

  • Oct 2018 - Aug 2022

  The role embraced science, business, and project management responsibilities:• Data analysis of complex chemical datasets• Management of drug discovery programs in early stage - identification of new hits and medicinal chemistry support to our partners• Scouting and building new partnerships in the global landscape • Keynote speaker at the most accredited drug discovery conferences• Company’s delegate for business conferences (eg BioEurope and BioPharm America)Despite the pandemic, during 2021 the company achieved a significant increase in the numbers of agreements signed (Europe and US), most of them came from an active partnership scouting. Show less

• Senior Scientist

  • May 2017 - Sep 2018

  Vipergen is a world leading provider of small molecule drug discovery services based on DNA-encoded library (DEL) technologies. As senior data analysis I had key roles in the generation of high-quality data for our partners (pharma and biotech companies worldwide):• Data analysis of complex chemical datasets coming from screening campaigns for different types of targets and many different therapeutic areas (oncology, inflammation, allergy, skin diseases etc…). It required the knowledge of cheminformatics tools, digital platforms and logical skills for an appropriate data interpretation.• Medicinal chemistry support to our partners• Communication with external partners and stakeholders • Project management Show less



SJI - Singapore

• Singapore

• Teaching position - chemistry

  • Jan 2016 - Apr 2017

  I have been teaching chemistry in one of the most prestigious colleges in Singapore, that prides itself on being the top country in the world in science education. Additional roles in the medicinal chemistry field: as lecturer and as facilitator of roundtable discussions (Medicinal chemistry strategy meeting APAC, 2016). • Teaching • People management I have been teaching chemistry in one of the most prestigious colleges in Singapore, that prides itself on being the top country in the world in science education. Additional roles in the medicinal chemistry field: as lecturer and as facilitator of roundtable discussions (Medicinal chemistry strategy meeting APAC, 2016). • Teaching • People management



Siena Biotech

• Project Leader

  • Sep 2010 - Aug 2014

  Leader of a multidisciplinary project aimed at the discovery of new S1P3 antagonists for the treatment of neurodegenerative diseases. • Drug Discovery project management • People management - medicinal chemistry and cross functional teams• FTEs allocation, accountability for milestone achievement, contribution to OPEX and external budget and coordination of internal and external activities (CRO and Academia)• Design and synthesis of new molecules starting from hits identified from HTS campaigns• SAR and ADMET data analysis Main project success: In a very short time, the project progressed from the screen to hit phase to the identification of lead molecules with promising ADMET profile and efficacy in two in vivo models (neurodegenerative and behavioral). Alternative (peripheral) applications were also investigated to improve chance for success and the project has since been out-licensed to a big pharma. Show less

• Scientist (Medicinal chemist)

  • Apr 2008 - Sep 2010

  Team member and chemist in the company flagship project aimed at the identification of agonists of the nAChR α7 receptor, as a potential treatment of Alzheimer’s disease and cognitive aspects of schizophrenia in an alliance with Wyeth Pharmaceuticals (now Pfizer). • Design and synthesis of CNS-penetrant small molecules• Coordinator of the chemistry group of the project (supervision of the design and synthesis of new molecules, relations with CROs and big pharma). • Drug Discovery project management • People management - medicinal chemistry teamChemistry leader for two main projects supported by European grants (European Commission FP6) aimed at disrupting Protein-Protein-Interaction: TWEAK/Fn14 (ADIT, grant no. LSHB-CT-2005-511977); MDM2/p53, MDMX/p53 (DePPICT, grant no. LSHC-CT2007-037834):• Coordination of internal and external chemistry activities • Interactions with other institutions part of the same EU grant (Academia and pharma) Show less



Siena Biotech & University of Siena

• Industrial Ph.D. Student

  • Apr 2004 - Mar 2008

  The PhD research was aimed at the design and synthesis of small molecules (antagonist of the 5-HT1A receptor) potentially useful for the treatment of psychiatric diseases. • Organic chemistry, medicinal chemistry and parallel synthesis for the preparation of focused libraries for drug discovery • Extensive wet-lab experience using traditional and modern apparatuses • Experience in the identification of Hit and Lead compounds; Lead optimisation; ADMET property evaluation; SAR definition Show less



Università di Siena - Career Service

• Professional Training and Coaching
• 500 - 600 Employee

• Researcher (Faculty of Pharmacy)

  • Jan 2003 - Mar 2004

  Organic chemist in the laboratories of Prof. Federico Corelli, University of Siena. • Basic organic chemistry research • Students’ supervision and mentoring • Support for the preparation of lectures and workshops Organic chemist in the laboratories of Prof. Federico Corelli, University of Siena. • Basic organic chemistry research • Students’ supervision and mentoring • Support for the preparation of lectures and workshops