Our core technology is surrounding Chimeric Antigen Receptor (CAR)-Natural Killer (NK) immunotherapy with ground-breaking allogeneic or ‘off-the-shelf’ expansion technology and a ‘first-in-class’ solid tumor molecular target-CD147. Our approach is to re-engineer NK cells-which belong to the human innate immune system to target the specific cancer cell surface marker CD147, and thereby kill the cancer cells more effectively and safely in comparison to existing treatments. To deliver this therapy cost-effectively and in a scalable way, we also have developed proprietary methods to expand ‘memory-like’, highly potent, ‘off-the-shelf’ NK and CAR-NK cells fast and with high purity. Our initial indication is hepatocellular carcinoma (HCC), a devastating solid tumor with marginally effective standard of care.
