Julie Clauss

Founder and CEO at Aptabridge Therapeutics at Aptabridge Therapeutics, Inc.
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Contact Information
Location
Cambridge, Massachusetts, United States, US
Languages
  • English Native or bilingual proficiency
  • French Native or bilingual proficiency

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Experience

    • United States
    • Biotechnology
    • 1 - 100 Employee
    • Founder and CEO at Aptabridge Therapeutics
      • Sep 2022 - Present
    • Vice President Gene Therapy Platform Lead
      • Aug 2021 - Sep 2022

      Responsible for defining the vision for Ultragenyx’s Gene Therapy (GT) function, overseeing the development of the global strategies and tactics that support the vision. Focus on driving and managing strong operational and strategic execution within the GT portfolio of products and working closely with markets and cross-functional partners on executing strategies and tactics. Responsible span from preparing the launch of our therapies in collaboration with our Commercial team to managing our gene therapy pipeline – including early-stage programs. Develop the Gene Therapy Business Strategic Vision and Mission, focusing on strategic decisions, investment opportunities or potential partnership including business development licensing deals, technology while proactively addressing risks/opportunities across the GT portfolio. Part of the GT leadership team, serve as a member of our extended senior leadership teams. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • MIT Sloan Fellows MBA
      • 2020 - 2021
    • United States
    • 1 - 100 Employee
    • Vice President, Head of R&D Operations
      • 2018 - 2020

      As an executive RDLT member of a healthcare organization focused on improving patients’ lives, I lead the development of the data driven global R&D strategy to implement critical R&D projects and initiatives aligned with Leadership Team objectives, managing a $400M R&D budget. I direct the execution of the project strategy in accordance with resource demand, funds, and risk factors, leading a team of 20 direct reports out of 700. I successfully drive an integrated planning culture within R&D, define a project-centric and value generating approach, and enable a clear and transparent cross-functional accountability. As the leader of portfolio and projects governance, I efficiently integrate data to assist in effective decision-making, while supporting R&D performance. Key Accomplishments: ● Built strategic portfolio management group across four R&D therapeutic areas and commercial franchises, delivering a unified vision, resulting in net sales of $3.0B. ● Implemented and supervise reporting capabilities and processes improving internal and external portfolio company communication. ● Collaborate cross-functionally in support of R&D functions, coordinating activities to facilitate project development and vision in alignment with portfolio strategy, overseeing methodology implementation, increasing ROI. ● Cultivate high performing project management team, leading the development of innovative strategies and advanced solutions to meet complex challenges, identifying areas for potential improvement, advancing portfolio to key decision points in timely manner, within available resources. Show less

    • Pharmaceutical Manufacturing
    • 200 - 300 Employee
    • Transformation Leader of Vaccines Development, Sr Director
      • 2016 - 2018

      I progressed through many roles within this company. In this position, I optimized my strong leadership and decision-making skills to launch a transversal transformational program for the Pasteur Global Business Unit, managing a project budget of $1.4M, leading a 35 member staff to improve business performance, driving the strategy to achieve best in class. I developed the critical elements of a vaccine roadmap and executed the global program development strategy including risk management, prioritizing and allocating valuable resources to meet key business targets. I also created the Development Vaccines governance to assist in decision-making. Key Accomplishments: ● Restructured CMC organization transforming staff focus and alignment of processes with Pasteur vision, achieving annual cost savings of 10%. ● Created cross-functional leaders’ community, collaborating in commitment to implementation of 2020 roadmap. ● Drove change management and cross-functional synergy serving as member of global leadership network. Show less

    • France
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Global R&D Organization redesign Leader
      • 2015 - 2016

      As an executive leader of a strategic global R&D reorganization design for 12 global therapeutic business units, impacting over 17,000 employees, managing a $4,0B budget, I was the driving force for creation of the new R&D organization. I collaborated with leadership and key stakeholders in the design of key benefits to add value and ultimately generate higher efficiency. As an effective change agent, I redesigned R&D processes, prepared and delivered a communication package sharing the R&D vision companywide. Show less

    • Chief of Staff of the Vice President Research & Translational Medicine
      • 2012 - 2015

      As a member of the research leadership team and review board, I developed a new research organization across 12 therapeutic units through the highly successful implementation of 300 diverse transversal projects, managing a $1.0B budget. I created a research model focused on patients, innovation, operational excellence, five-year research budget plan, research portfolio, and prioritization. I also launched a worldwide research communication campaign with Biotech and Michael J. Fox foundation CEOs. Show less

    • Business Process & Performance Manager
      • 2011 - 2012

      As an innovative project manager, I led the R&D management office organization, R&D portfolio management, BI reporting process, and key dashboards to assist with portfolio decision-making. I efficiently gathered data from multiple sources to research economic indicators, analyze key metrics, and track industry trends, creating analyses to ensure long-term efficiency and growth. As a process manager, I drove key transversal projects through optimized governance models, analyzed systems functions and reporting processes, improving efficiency and productivity of R&D organization. Show less

    • Head of Processes and Projects for Industrial Purchasing Worldwide
      • 2008 - 2011

      In this position, I was the strategic leader of 20 global process improvement projects for worldwide industrial procurement, covering 106 manufacturing sites in 40 countries. I created and implemented projects to improve purchasing process and tool development, leading a team of 20, ensuring quality cross-sharing information.

    • Project leader & Business partner for IT
      • 2004 - 2007

      In this role, I defined and contributed to the roll out of Sanofi Manufacturing System (ERP) for 110 manufacturing sites, integrating with group systems, and key member of SAP/Oracle projects, conducting training sessions to ensure successful implementation. I implemented five industrial sites in France and Hungary managing a budget of $2.4M per site, defining and harmonizing all functional processes. I also contributed to the strategy definition for IS processes and tools. In this role, I defined and contributed to the roll out of Sanofi Manufacturing System (ERP) for 110 manufacturing sites, integrating with group systems, and key member of SAP/Oracle projects, conducting training sessions to ensure successful implementation. I implemented five industrial sites in France and Hungary managing a budget of $2.4M per site, defining and harmonizing all functional processes. I also contributed to the strategy definition for IS processes and tools.

Education

  • MIT Sloan School of Management
    Master of Business Administration - MBA Fellowship
    2020 - 2021
  • Ecole Centrale de Marseille
    Master of Engineering - MEng, Chemical synthesis, Industrial Processes, General engineering
    2002 - 2004
  • Université Joseph Fourier (Grenoble I)
    Master of Sciences, Chemistry, Physical Sciences
    1998 - 2002
  • Université Joseph Fourier
    Bachelor's degree, Chemistry

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