Daniel Urul

Senior R&D Scientist at AssayQuant Technologies
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Contact Information
Location
Framingham, Massachusetts, United States, US
Languages
  • English Native or bilingual proficiency
  • Turkish Native or bilingual proficiency
  • Spanish Limited working proficiency

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Bio

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior R&D Scientist
      • May 2021 - Present
    • United States
    • Higher Education
    • 700 & Above Employee
    • PhD Graduate Student
      • Aug 2015 - Dec 2020

      As an NSF GRFP fellow, my doctoral work focused on the adaptation and expansion of proteomic profiling techniques to identify endogenous reactive electrophilic species (RES) sensors in C. elegans. By utilizing novel methods to uncover native RES sensors in a well-characterized whole-organism model, this work seeks to establish a new avenue for deepening our comprehension of RES-mediated signaling pathways with relevance to human biology and covalent drug development. • Adapted a novel… Show more As an NSF GRFP fellow, my doctoral work focused on the adaptation and expansion of proteomic profiling techniques to identify endogenous reactive electrophilic species (RES) sensors in C. elegans. By utilizing novel methods to uncover native RES sensors in a well-characterized whole-organism model, this work seeks to establish a new avenue for deepening our comprehension of RES-mediated signaling pathways with relevance to human biology and covalent drug development. • Adapted a novel toolset for interrogating redox-sensing functionality of target proteins (T-REX) for in vivo utilization in C. elegans (ACS Biochemistry 2018; Current Protocols in Chemical Biology 2018) • Worked to expand the REX toolset in C. elegans into a platform for interrogating the redox-sensing cysteinome (Methods in Enzymology 2019; +1 manuscript in preparation) • Characterized redox modification and signaling functionality in newly identified RES-sensor proteins (ACS Chemical Biology 2018; +1 manuscript in preparation)

    • Graduate Teaching Assistant
      • Aug 2015 - Dec 2016

      Directed practical laboratory sessions, graded reports and exams, and held office hour discussions for undergraduate students. • Fall 2016: Chemical Biology – Proctor and grader for problem sets and exams of a class of ~20 students. • Spring 2016: Organic Chemistry Lab – Conducted 2 weekly lab sections, held office hours, and proctored/graded lab practicals and written exams. • Fall 2015: General Chemistry Lab – Conducted 2 weekly lab sections, held office hours, and graded… Show more Directed practical laboratory sessions, graded reports and exams, and held office hour discussions for undergraduate students. • Fall 2016: Chemical Biology – Proctor and grader for problem sets and exams of a class of ~20 students. • Spring 2016: Organic Chemistry Lab – Conducted 2 weekly lab sections, held office hours, and proctored/graded lab practicals and written exams. • Fall 2015: General Chemistry Lab – Conducted 2 weekly lab sections, held office hours, and graded exams/assignments.

    • Switzerland
    • Higher Education
    • 700 & Above Employee
    • Visiting PhD Graduate Student
      • Jan 2019 - Apr 2020

      Continued graduate work with Prof. Yimon Aye as a visiting researcher in Lausanne, Switzerland, during the Aye Lab's transition from Cornell to EPFL. • Facilitated transfer of our group's C. elegans material and associated laboratory setup, as well as our fluorescent stereomicroscopy equipment, as part of the Aye Lab's overseas relocation. • Collaborated with several EPFL-affiliated groups while re-establishing and refining our group's C. elegans research program. • Mentored an… Show more Continued graduate work with Prof. Yimon Aye as a visiting researcher in Lausanne, Switzerland, during the Aye Lab's transition from Cornell to EPFL. • Facilitated transfer of our group's C. elegans material and associated laboratory setup, as well as our fluorescent stereomicroscopy equipment, as part of the Aye Lab's overseas relocation. • Collaborated with several EPFL-affiliated groups while re-establishing and refining our group's C. elegans research program. • Mentored an MS-level EPFL student in C. elegans handling and experimental techniques, as well as associated chemical biology protocols, culminating in essential contributions to a current manuscript in preparation Show less Continued graduate work with Prof. Yimon Aye as a visiting researcher in Lausanne, Switzerland, during the Aye Lab's transition from Cornell to EPFL. • Facilitated transfer of our group's C. elegans material and associated laboratory setup, as well as our fluorescent stereomicroscopy equipment, as part of the Aye Lab's overseas relocation. • Collaborated with several EPFL-affiliated groups while re-establishing and refining our group's C. elegans research program. • Mentored an… Show more Continued graduate work with Prof. Yimon Aye as a visiting researcher in Lausanne, Switzerland, during the Aye Lab's transition from Cornell to EPFL. • Facilitated transfer of our group's C. elegans material and associated laboratory setup, as well as our fluorescent stereomicroscopy equipment, as part of the Aye Lab's overseas relocation. • Collaborated with several EPFL-affiliated groups while re-establishing and refining our group's C. elegans research program. • Mentored an MS-level EPFL student in C. elegans handling and experimental techniques, as well as associated chemical biology protocols, culminating in essential contributions to a current manuscript in preparation Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Technical Reader/Assistant
      • Aug 2014 - Jul 2015

      Assisted a blind graduate student in the Merz computational biochemistry group (affiliated with the UF Quantum Theory Project) in various roles, including document reading/writing, molecular visualization, and clerical work. During this time, I gained experience with basic bioinformatics methodology and computational biology principles.

    • Undergraduate Research Assistant
      • Jun 2011 - Jul 2014

      Under the direction of Professor Steven Bruner, I conducted structural analysis of novel proteins through fusion protein engineering, site-specific mutagenesis, diffusion crystallography, and computational structural prediction.

Education

  • Cornell University
    Doctor of Philosophy - PhD, Chemical Biology
    2015 - 2020
  • Cornell University
    Master's degree, Chemical Biology
    2015 - 2017
  • University of Florida
    Bachelor's Degree, Chemistry
    2010 - 2014
  • Fleming Island High School
    High School Diploma
    2006 - 2010

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